2024
Non-dominant, Tumor-related Temporal Lobe Epilepsy
Herlopian A. Non-dominant, Tumor-related Temporal Lobe Epilepsy. 2024, 161-174. DOI: 10.1007/978-3-031-23828-4_8.Peer-Reviewed Original ResearchTumor-related epilepsyTumor-related temporal lobe epilepsyPredictor of post-operative outcomesIntra-operative electrocorticographyPost-operative outcomesPre-surgical evaluationTemporal lobe epilepsySurgical approachAdult patientsElectroencephalographic evaluationSemiological differencesMR spectroscopyLobe epilepsyNeuroimaging findingsEpilepsyPatientsLesionsLoss of awareness
2011
OT3-01-03: Pre-Surgical Evaluation of the AKT Inhibitor MK-2206 in Patients with Operable Invasive Breast Cancer: New York Cancer Consortium Trial P8740.
Kalinsky K, Sparano J, Kim M, Crew K, Maurer M, Taback B, Feldman S, Hibshoosh H, Wiechmann L, Adelson K, Hershman D. OT3-01-03: Pre-Surgical Evaluation of the AKT Inhibitor MK-2206 in Patients with Operable Invasive Breast Cancer: New York Cancer Consortium Trial P8740. Cancer Research 2011, 71: ot3-01-03-ot3-01-03. DOI: 10.1158/0008-5472.sabcs11-ot3-01-03.Peer-Reviewed Original ResearchPre-surgical studyInvasive breast cancerBreast cancerPI3K/AktWeekly MKPost-treatment tissue samplesOperable invasive breast cancerPeripheral blood mononuclear cellsEarly phase clinical studiesDownstream PI3K/Akt pathwayClinical stage IClinical trial programBlood mononuclear cellsMain eligibility criteriaPre-surgical evaluationEarly clinical testingPI3K/Akt pathwayEffects of MKAKT inhibitor MKPost-treatment samplesAnti-cancer propertiesParaffin-embedded tissuesAccrue patientsAnti-cancer agentsNeoadjuvant chemotherapy
2009
Frequency, prognosis and surgical treatment of structural abnormalities seen with magnetic resonance imaging in childhood epilepsy
Berg AT, Mathern GW, Bronen RA, Fulbright RK, DiMario F, Testa FM, Levy SR. Frequency, prognosis and surgical treatment of structural abnormalities seen with magnetic resonance imaging in childhood epilepsy. Brain 2009, 132: 2785-2797. PMID: 19638447, PMCID: PMC2759335, DOI: 10.1093/brain/awp187.Peer-Reviewed Original ResearchMeSH KeywordsAdolescentAge of OnsetAnticonvulsantsBrainChildChild, PreschoolCognitionCohort StudiesDrug ResistanceEpilepsyFemaleFunctional LateralityHumansImage Processing, Computer-AssistedInfantLogistic ModelsMagnetic Resonance ImagingMaleNeurologic ExaminationNeuropsychological TestsNeurosurgical ProceduresPrognosisSclerosisTomography, X-Ray ComputedConceptsMagnetic resonance imagingPositive MRI scansEpilepsy patientsMRI scansEpilepsy syndromesEpilepsy evaluationSurgical proceduresMultiple logistic regression analysisUse of MRIComprehensive epilepsy evaluationNon-idiopathic patientsPediatric epilepsy patientsComprehensive Epilepsy CenterPositive MRI findingsCommunity-based cohortNormal neurological examPre-surgical evaluationLogistic regression analysisIdiopathic epilepsy syndromesFrequency of lesionsClinical factorsMRI abnormalitiesMRI findingsNeurological examSurgical treatment
2007
To Sleep, Perchance to Seize: Surgery Ameliorates Nocturnal Frontal Lobe Seizures
Hirsch LJ. To Sleep, Perchance to Seize: Surgery Ameliorates Nocturnal Frontal Lobe Seizures. Epilepsy Currents 2007, 8: 12-14. PMID: 18265881, PMCID: PMC2238651, DOI: 10.1111/j.1535-7511.2007.00219.x.Peer-Reviewed Original ResearchFocal cortical dysplasiaExcessive daytime sleepinessPre-surgical evaluationSleep-related seizuresFrontal lobe seizuresEpileptogenic zoneStereo-EEGFrontal lobeAccurate pre-surgical evaluationComprehensive pre-surgical evaluationScalp video-EEG monitoringTaylor's focal cortical dysplasiaClass IIDrug-resistant focal epilepsyTaylor-type focal cortical dysplasiaEngel class IAEngel Class IIIctal clinical signsNocturnal frontal lobe epilepsyVideo-EEG monitoringClass IaFrontal lobe originNocturnal frontal lobe seizuresFrontal lobe epilepsyInvasive EEG recordings
1995
Functional MRI measurement of language Lateralization in Wada-tested patients
Desmond J, Sum J, Wagner A, Demb J, Shear P, Glover G, Gabrieli J, Morrell M. Functional MRI measurement of language Lateralization in Wada-tested patients. Brain 1995, 118: 1411-1419. PMID: 8595473, DOI: 10.1093/brain/118.6.1411.Peer-Reviewed Original ResearchConceptsLanguage lateralizationFunctional MRIPerceptual judgmentsHuman cognitive processesInferior frontal gyrusBrodmann area 45Functional MRI measurementsHemispheric language dominanceCognitive processesSemantic relativeFrontal gyrusLanguage dominanceFMRI scansArea 45LateralizationTemporal lobe epilepsyJudgmentsOrbital cortexPre-surgical evaluationLobe epilepsyNon-invasive measureTest assessmentSignificant clinical potentialPatientsGyrus
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