2001
Extracellular ATP effects on calcium signaling in cultured human non-pigmented ciliary body epithelium
Cullinane A, Coca-Prados M, Harvey B. Extracellular ATP effects on calcium signaling in cultured human non-pigmented ciliary body epithelium. Current Eye Research 2001, 23: 448-454. PMID: 12045895, DOI: 10.1076/ceyr.23.6.448.6964.Peer-Reviewed Original ResearchMeSH KeywordsAdenosine TriphosphateCalciumCalcium-Transporting ATPasesCells, CulturedCiliary BodyFluorescent DyesFura-2HumansMicroscopy, FluorescencePigment Epithelium of EyeReceptors, Purinergic P2Receptors, Purinergic P2Y2Signal TransductionSodium-Calcium ExchangerSpectrometry, FluorescenceThapsigarginConceptsNon-pigmented ciliary body epitheliumCiliary body epitheliumHNPE cellsIntracellular storesBody epitheliumFluorescent dye fura-2Extracellular ATP effectP2Y2 receptor activationDye fura-2Calcium signalsATPase pumpPresence of thapsigarginCapacitative calcium entrySodium-free solutionIntracellular calciumPurinergic receptorsFura-2Therapeutic targetCalcium entryPotency orderReceptor activationSustained increaseL-typeExtracellular ATPOscillatory increases
1994
Endothelin-1 conversion and receptor characterization in human placental arteries
Wilkes B, Macica C, Mento P. Endothelin-1 conversion and receptor characterization in human placental arteries. American Journal Of Physiology 1994, 267: e242-e249. PMID: 8074203, DOI: 10.1152/ajpendo.1994.267.2.e242.Peer-Reviewed Original ResearchConceptsFetoplacental blood vesselsEndothelin-1Big endothelin-1Blood vesselsHuman placental arteriesEndothelin receptor subtypesEndothelin-1 receptorsAtrial natriuretic factorTime-dependent increasePlacental arteriesSpecific receptor sitesPerfusion pressureAngiotensin IIEndothelin receptorsNatriuretic factorReceptor subtypesSmall arteriesPlacental cotyledonsPotency orderFmol/High-affinity binding sitesBig endothelinReceptor characterizationScatchard analysisPressor peptide
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