2025
Predicting White Matter Hyperintensity: Leveraging Portable Magnetic Resonance Imaging for Accessible Brain Health Screening.
Johnson I, Brigger H, Smith J, Peasley E, Champagne A, Littig L, Lalwani D, Sze G, Payabvash S, Safdar B, D'Onofrio G, Wira C, Iglesias J, Rosen M, Sorby-Adams A, Kimberly W, Sheth K, de Havenon A. Predicting White Matter Hyperintensity: Leveraging Portable Magnetic Resonance Imaging for Accessible Brain Health Screening. American Journal Of Neuroradiology 2025, ajnr.a8734. PMID: 40081846, DOI: 10.3174/ajnr.a8734.Peer-Reviewed Original ResearchWhite matter hyperintensitiesWMH measuresMagnetic resonance imagingConventional MRIScreening pilot programRisk factorsValidation cohortHigh-risk individualsAcute neurologic pathologyVascular risk factorsTertiary care hospitalSystolic blood pressure >Resonance imagingDevelopment cohortWhite matter hyperintensities burdensHealth screeningTobacco useBlood pressure >Emergency departmentCare hospitalPortable MRIRisk scoreScreening toolPilot programPrimary outcome
2024
Quantifying White Matter Hyperintensity and Brain Volumes in Heterogeneous Clinical and Low-Field Portable MRI
Laso P, Cerri S, Sorby-Adams A, Guo J, Mateen F, Goebl P, Wu J, Liu P, Li H, Young S, Billot B, Puonti O, Sze G, Payabavash S, DeHavenon A, Sheth K, Rosen M, Kirsch J, Strisciuglio N, Wolterink J, Eshaghi A, Barkhof F, Kimberly W, Iglesias J. Quantifying White Matter Hyperintensity and Brain Volumes in Heterogeneous Clinical and Low-Field Portable MRI. 2024, 00: 1-5. DOI: 10.1109/isbi56570.2024.10635502.Peer-Reviewed Original Research
2023
Portable MRI to assess optic chiasm decompression after endoscopic endonasal resection of sellar and suprasellar lesions.
Hong C, Lamsam L, Yadlapalli V, Parasuram N, Mazurek M, Chavva I, Lalwani D, Zabinska J, Schiff S, Manes R, Vining E, Rimmer R, Kimberly W, Sheth K, Omay S. Portable MRI to assess optic chiasm decompression after endoscopic endonasal resection of sellar and suprasellar lesions. Journal Of Neurosurgery 2023, 139: 1664-1670. PMID: 37347618, DOI: 10.3171/2023.5.jns23174.Peer-Reviewed Original ResearchConceptsEndoscopic endonasal surgeryOptic nerve decompressionEndonasal surgerySuprasellar lesionsNerve decompressionOptic chiasmThird ventricleConventional MRIOptic chiasm compressionEndoscopic endonasal resectionChiasm compressionPreoperative imagingSingle institutionEndonasal resectionMRI availabilityRoutine MRISignificant interrater reliabilitySuprasellar pathologiesSurgeryNeurosurgical oncologyLinear mixed-effects modelsPortable MRIPatientsMRIMixed-effects modelsPortable MRI to Assess Optic Nerve Decompression after Endoscopic Endonasal Resection of Sellar Lesions
Hong C, Lamsam L, Crawford A, Sheth K, Rimmer R, Omay S. Portable MRI to Assess Optic Nerve Decompression after Endoscopic Endonasal Resection of Sellar Lesions. Journal Of Neurological Surgery Part B Skull Base 2023, 84: s1-s344. DOI: 10.1055/s-0043-1762183.Peer-Reviewed Original Research
2022
Bedside detection of intracranial midline shift using portable magnetic resonance imaging
Sheth KN, Yuen MM, Mazurek MH, Cahn BA, Prabhat AM, Salehi S, Shah JT, By S, Welch EB, Sofka M, Sacolick LI, Kim JA, Payabvash S, Falcone GJ, Gilmore EJ, Hwang DY, Matouk C, Gordon-Kundu B, RN AW, Petersen N, Schindler J, Gobeske KT, Sansing LH, Sze G, Rosen MS, Kimberly WT, Kundu P. Bedside detection of intracranial midline shift using portable magnetic resonance imaging. Scientific Reports 2022, 12: 67. PMID: 34996970, PMCID: PMC8742125, DOI: 10.1038/s41598-021-03892-7.Peer-Reviewed Original ResearchConceptsMidline shiftNeuroscience intensive care unitCare measurementYale-New Haven HospitalValuable bedside toolIntensive care unitPoor clinical outcomeBrain-injured patientsMass effectNew Haven HospitalMagnetic resonance imagingClinical outcomesIll patientsCare unitStroke patientsFunctional outcomeBedside toolObservational studyBedside detectionImaging examsPatientsResonance imagingPortable MRIImaging suiteSignificant concordance
2021
Portable, bedside, low-field magnetic resonance imaging for evaluation of intracerebral hemorrhage
Mazurek MH, Cahn BA, Yuen MM, Prabhat AM, Chavva IR, Shah JT, Crawford AL, Welch EB, Rothberg J, Sacolick L, Poole M, Wira C, Matouk CC, Ward A, Timario N, Leasure A, Beekman R, Peng TJ, Witsch J, Antonios JP, Falcone GJ, Gobeske KT, Petersen N, Schindler J, Sansing L, Gilmore EJ, Hwang DY, Kim JA, Malhotra A, Sze G, Rosen MS, Kimberly WT, Sheth KN. Portable, bedside, low-field magnetic resonance imaging for evaluation of intracerebral hemorrhage. Nature Communications 2021, 12: 5119. PMID: 34433813, PMCID: PMC8387402, DOI: 10.1038/s41467-021-25441-6.Peer-Reviewed Original ResearchConceptsMagnetic resonance imagingNIH Stroke ScaleIntracerebral hemorrhageHematoma volumeYale-New Haven HospitalStroke care pathwayConventional magnetic resonance imagingBoard-certified neuroradiologistsNew Haven HospitalResource-limited settingsStroke ScaleClinical outcomesLow-field magnetic resonance imagingCare pathwayLow-field magnetic resonanceRadiological examinationConventional neuroimagingAdvanced MRI technologiesResonance imagingCases of disagreementHemorrhageMRI technologyPortable MRINeuroimagingMagnetic resonance
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