2021
Personalised, Rational, Efficacy-Driven Cancer Drug Dosing via an Artificial Intelligence SystEm (PRECISE): A Protocol for the PRECISE CURATE.AI Pilot Clinical Trial
Tan B, Teo C, Tadeo X, Peng S, Soh H, Du S, Luo V, Bandla A, Sundar R, Ho D, Kee T, Blasiak A. Personalised, Rational, Efficacy-Driven Cancer Drug Dosing via an Artificial Intelligence SystEm (PRECISE): A Protocol for the PRECISE CURATE.AI Pilot Clinical Trial. Frontiers In Digital Health 2021, 3: 635524. PMID: 34713106, PMCID: PMC8521832, DOI: 10.3389/fdgth.2021.635524.Peer-Reviewed Original ResearchTumor marker levelsRandomised controlled trialsDrug dosePersonalised dosingSolid tumorsMarker levelsNational Healthcare GroupSignificant dose changesCapecitabine-based chemotherapyMetastatic solid tumorsDose of drugOpen-labelChemotherapy doseDose changesDosing recommendationsCohort expansionSingle-armSuboptimal efficacyProportion of participantsPrimary outcomeSecondary outcomesInterim analysisPhysician adherenceControlled TrialsPrecision oncology
2019
Climate change and quality of health care: evidence from extreme heat
Si Y, Zhou Z, Su M, Chen X. Climate change and quality of health care: evidence from extreme heat. The Lancet 2019, 394: s94. DOI: 10.1016/s0140-6736(19)32430-4.Peer-Reviewed Original ResearchCommunity health centersClinical checklistHealth centersHealth careNational InstituteQuality of careHealth service deliveryNecessary health servicesXi'an Jiaotong UniversityAccuracy of diagnosisPhysician adherencePhysical examinationPrimary careAppropriate treatmentCorrect diagnosisPatientsHealth servicesPhysiciansCareMean numberAdherenceMedical boardsImproved qualityStandardised patientsChecklist items
2018
Clinical Decision Support for Ordering CTA-PE Studies in the Emergency Department—A Pilot on Feasibility and Clinical Impact in a Tertiary Medical Center
Goehler A, Moore C, Manne-Goehler JM, Arango J, D'Amato L, Forman HP, Weinreb J. Clinical Decision Support for Ordering CTA-PE Studies in the Emergency Department—A Pilot on Feasibility and Clinical Impact in a Tertiary Medical Center. Academic Radiology 2018, 26: 1077-1083. PMID: 30389307, DOI: 10.1016/j.acra.2018.09.009.Peer-Reviewed Original ResearchConceptsPulmonary embolismClinical decision supportPositivity rateTertiary medical centerComputed tomography angiographyPhysician adherenceD-dimerGood discriminatory powerTomography angiographyEmergency providersClinical impactMedical CenterRisk scoreDiscriminatory powerEmbolismPatientsAngiographyComplianceStudy
2017
Physician Decisions to Defer Antiretroviral Therapy in Key Populations: Implications for Reducing Human Immunodeficiency Virus Incidence and Mortality in Malaysia
Ferro EG, Culbert GJ, Wickersham JA, Marcus R, Steffen AD, Pauls HA, Westergaard RP, Lee CK, Kamarulzaman A, Altice FL. Physician Decisions to Defer Antiretroviral Therapy in Key Populations: Implications for Reducing Human Immunodeficiency Virus Incidence and Mortality in Malaysia. Open Forum Infectious Diseases 2017, 4: ofw219. PMID: 28480230, PMCID: PMC5414088, DOI: 10.1093/ofid/ofw219.Peer-Reviewed Original ResearchHuman immunodeficiency virusT-cell countsAdvanced human immunodeficiency virusAntiretroviral therapyKey risk populationsKey populationsRisk populationsEvidence-based treatment guidelinesHuman immunodeficiency virus (HIV) incidenceClinician-level interventionsHypothetical clinical scenariosProportion of physiciansHigher CD4HIV patientsPhysician adherenceControl patientsTreatment guidelinesHIV incidenceImmunodeficiency virusART accessART coverageInternet-based surveyPhysicians' attitudesPrevention strategiesClinical scenarios
2013
Treatment Differences by Health Insurance Among Outpatients With Coronary Artery Disease Insights From the National Cardiovascular Data Registry
Smolderen KG, Spertus JA, Tang F, Oetgen W, Borden WB, Ting HH, Chan PS. Treatment Differences by Health Insurance Among Outpatients With Coronary Artery Disease Insights From the National Cardiovascular Data Registry. Journal Of The American College Of Cardiology 2013, 61: 1069-1075. PMID: 23375933, PMCID: PMC3641586, DOI: 10.1016/j.jacc.2012.11.058.Peer-Reviewed Original ResearchMeSH KeywordsAdrenergic beta-AntagonistsAmbulatory CareAngiotensin Receptor AntagonistsAngiotensin-Converting Enzyme InhibitorsCoronary Artery DiseaseDrug UtilizationFemaleHumansHypolipidemic AgentsInsurance, HealthMaleMedicaidMedically UninsuredMedicareMiddle AgedPlatelet Aggregation InhibitorsRegistriesUnited StatesUnited States Department of Veterans AffairsUnited States Indian Health ServiceConceptsCoronary artery diseaseUninsured patientsEvidence-based treatmentsInsurance statusARB therapyAngiotensin-converting enzyme inhibitors/angiotensin II receptor blockersEnzyme inhibitors/angiotensin II receptor blockersAngiotensin II receptor blockersNational Cardiovascular Data RegistryPublic insuranceEvidence-based medicationsLipid-Lowering TherapyII receptor blockersLeft ventricular dysfunctionHealth insuranceTreatment differencesPoisson regression modelsPINNACLE RegistryPhysician adherenceVentricular dysfunctionReceptor blockersArtery diseaseCardiac RegistryCardiac outpatientsData registry
2000
A Guideline Implementation System Using Handheld Computers for Office Management of Asthma: Effects on Adherence and Patient Outcomes
Shiffman R, Freudigman M, Brandt C, Liaw Y, Navedo D. A Guideline Implementation System Using Handheld Computers for Office Management of Asthma: Effects on Adherence and Patient Outcomes. 2000, 105: 767-773. PMID: 10742318, DOI: 10.1542/peds.105.4.767.Peer-Reviewed Original ResearchConceptsIntervention phaseAsthma exacerbationsPatient outcomesAmerican AcademySubsequent emergency department visitsPeak expiratory flow rateGuideline implementation systemsAcute asthma exacerbationEmergency department visitsExpiratory flow rateOutcomes of careTelephone 7Physician adherenceDepartment visitsGuideline recommendationsOffice managementPediatric guidelinesGuideline-based decision supportOxygen saturationPatient encountersEncounter documentationVisitsPost visitExacerbationOutcomes
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