2010
Intrahippocampal LSD accelerates learning and desensitizes the 5-HT2A receptor in the rabbit, Romano et al.
Romano AG, Quinn JL, Li L, Dave KD, Schindler EA, Aloyo VJ, Harvey JA. Intrahippocampal LSD accelerates learning and desensitizes the 5-HT2A receptor in the rabbit, Romano et al. Psychopharmacology 2010, 212: 441-448. PMID: 20827462, DOI: 10.1007/s00213-010-2004-7.Peer-Reviewed Original ResearchConceptsDorsal hippocampusDevelopment of desensitizationD-lysergic acid diethylamideEyeblink conditioningChronic administrationAminopropane hydrochlorideLast infusionIntrahippocampal injectionReceptor agonistParenteral injectionSerotonin 5HippocampusTrace eyeblink conditioningAcid diethylamideReceptorsPavlovian conditioningConditioning sessionsVehicle controlInjectionAgonists
2006
Neurobiology of anxiety disorders and implications for treatment.
Garakani A, Mathew SJ, Charney DS. Neurobiology of anxiety disorders and implications for treatment. Annals Of Global Health 2006, 73: 941-9. PMID: 17195879.Peer-Reviewed Reviews, Practice Guidelines, Standards, and Consensus StatementsConceptsPost-traumatic stress disorderCognitive behavioral therapyFear conditioningUnconditioned stimulusAnxiety disordersPartial NMDA agonistFear inhibitionFear extinctionTraumatic memoriesFear circuitryFear responsesPavlovian conditioningBehavioral therapyStress disorderSpecific phobiaNew learningAmygdala pathwayD-cycloserineAnti-anxiety treatmentPanic disorderPreliminary evidenceStimuliMemoryN-methyl-D-aspartate antagonistsNeurobiology
2005
Time-limited modulation of appetitive Pavlovian memory by D1 and NMDA receptors in the nucleus accumbens
Dalley J, Lääne K, Theobald D, Armstrong H, Corlett P, Chudasama Y, Robbins T. Time-limited modulation of appetitive Pavlovian memory by D1 and NMDA receptors in the nucleus accumbens. Proceedings Of The National Academy Of Sciences Of The United States Of America 2005, 102: 6189-6194. PMID: 15833811, PMCID: PMC556132, DOI: 10.1073/pnas.0502080102.Peer-Reviewed Original ResearchConceptsAppetitive Pavlovian learningEarly memory consolidationNMDA receptor antagonistNucleus accumbensPavlovian memoryPavlovian learningAppetitive learningAssociative processesMemory consolidationApproach behaviorInstrumental learningPavlovian conditioningAppetitive memoryFood rewardReceptor antagonistConditioning sessionsNMDA receptorsSpatial learningInstrumental processesGlutamatergic influencesEarly consolidationD2 receptor antagonist sulpirideReceptor antagonist sulpirideIntra-NAc infusionsLearning
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