2018
Rhythmicity and waves in the cortex of single cells
Yang Y, Wu M. Rhythmicity and waves in the cortex of single cells. Philosophical Transactions Of The Royal Society B Biological Sciences 2018, 373: 20170116. PMID: 29632268, PMCID: PMC5904302, DOI: 10.1098/rstb.2017.0116.Peer-Reviewed Reviews, Practice Guidelines, Standards, and Consensus StatementsConceptsDifferent dynamical statesDynamical stateDynamic systemsForm of oscillationsBasic propertiesSpatial couplingNetwork-centric viewSingle cellsPattern formationWavesCellular functionsTheme issueCell biologyMore mechanistic studiesCellular organizationFunctional importanceDynamic patternsEnigmatic phenomenonMolecular definitionKey parametersOscillations
2017
Clathrin Assembly Defines the Onset and Geometry of Cortical Patterning
Yang Y, Xiong D, Pipathsouk A, Weiner OD, Wu M. Clathrin Assembly Defines the Onset and Geometry of Cortical Patterning. Developmental Cell 2017, 43: 507-521.e4. PMID: 29161594, PMCID: PMC5826602, DOI: 10.1016/j.devcel.2017.10.028.Peer-Reviewed Original ResearchConceptsPlasma membraneClathrin assemblyClathrin functionEndocytic proteinsMembrane traffickingEndocytic machineryN-WASPEndocytic eventsSignal transductionDownstream factorsCell surfaceCortical patterningPattern formationAssemblyMembraneImportant insightsActive processSingle-cell patternFBP17Cdc42ClathrinEndocytosisTransductionCortical pattern formationPhosphatidylinositol
2010
Regulation of blood vessel patterning and guidance
Eichmann A. Regulation of blood vessel patterning and guidance. The FASEB Journal 2010, 24: 62.3-62.3. DOI: 10.1096/fasebj.24.1_supplement.62.3.Peer-Reviewed Original ResearchVertebrate embryonic developmentBlood vessel patterningLigand-receptor interactionsKey ligand-receptor interactionsVertebrate embryosVessel patterningZebrafish embryosPrimitive tubeGrowth factor gradientsEmbryonic developmentMesodermal cellsMajor axial vesselsMolecular mechanismsStereotyped architectureVascular developmentVascular systemSimilar branching patternsFactor gradientsCardinal veinEmbryosPrimitive vesselsBranched networkPattern formationEndothelial cellsHemodynamic forces
2009
CVP2‐ and CVL1‐mediated phosphoinositide signaling as a regulator of the ARF GAP SFC/VAN3 in establishment of foliar vein patterns
Carland F, Nelson T. CVP2‐ and CVL1‐mediated phosphoinositide signaling as a regulator of the ARF GAP SFC/VAN3 in establishment of foliar vein patterns. The Plant Journal 2009, 59: 895-907. PMID: 19473324, DOI: 10.1111/j.1365-313x.2009.03920.x.Peer-Reviewed Original ResearchConceptsPleckstrin homology domainVein phenotypeCell polarityHomology domainSpecific phosphoinositideADP-ribosylation factor GTPaseVein pattern formationIntracellular vesicle transportPlant ArabidopsisVesicle trafficLeaf developmentVesicle cargoVesicle transportVAN3Animal cellsFoliar organsPhosphoinositidePi-ligandCellular sitesMutantsPattern formationMutationsCvp2PhenotypeRecent evidence
1998
AP-2-null cells disrupt morphogenesis of the eye, face, and limbs in chimeric mice
Nottoli T, Hagopian-Donaldson S, Zhang J, Perkins A, Williams T. AP-2-null cells disrupt morphogenesis of the eye, face, and limbs in chimeric mice. Proceedings Of The National Academy Of Sciences Of The United States Of America 1998, 95: 13714-13719. PMID: 9811866, PMCID: PMC24885, DOI: 10.1073/pnas.95.23.13714.Peer-Reviewed Original ResearchConceptsAP-2Neural tubePleiotropic developmental abnormalitiesAP-2 geneCritical new roleLimb pattern formationRange of phenotypesBody wallLethal phenotypeKnockout miceMorphogenic pathwaysChimeric miceEye formationDevelopmental mechanismsHomozygous disruptionLimb duplicationsTeratogenic levelsDefective developmentDevelopmental abnormalitiesRetinoic acidPhenotypeMechanism of actionIndependent requirementsPattern formationChimerasHanded asymmetry in the mouse: Understanding how things go right (or left) by studying how they go wrong
Supp D, Brueckner M, Potter S. Handed asymmetry in the mouse: Understanding how things go right (or left) by studying how they go wrong. Seminars In Cell And Developmental Biology 1998, 9: 77-87. PMID: 9572117, DOI: 10.1006/scdb.1997.0186.Peer-Reviewed Original ResearchConceptsSevere morphological defectsAnalysis of genesAsymmetric expression patternLeft/right axisRight patterningGenetic pathwaysMouse mutationExpression patternsMorphological defectsDevelopmental asymmetryVertebratesImportance of regulationMutant micePattern formationRight axisGenesMutationsRegulationPathwayPatterningMiceDisruption
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