2016
Cell–cell communication enhances the capacity of cell ensembles to sense shallow gradients during morphogenesis
Ellison D, Mugler A, Brennan MD, Lee SH, Huebner RJ, Shamir ER, Woo LA, Kim J, Amar P, Nemenman I, Ewald AJ, Levchenko A. Cell–cell communication enhances the capacity of cell ensembles to sense shallow gradients during morphogenesis. Proceedings Of The National Academy Of Sciences Of The United States Of America 2016, 113: e679-e688. PMID: 26792522, PMCID: PMC4760786, DOI: 10.1073/pnas.1516503113.Peer-Reviewed Original ResearchConceptsCell-cell communicationCollective cell responseEpidermal growth factor (EGF) gradientsCell-cell interactionsGradient sensingMammary epithelial cellsSignaling inputsSingle-cell sensitivityGrowth factor gradientsIntegrative analysisIntercellular communicationCell ensemblesChemotactic cuesMulticellular sensingFunctional experimentsFactor gradientsSingle cellsGap junctionsEpithelial cellsTissue formEffective sizeExogenous cuesIntracellular storesCellsComplex changes
2010
Regulation of blood vessel patterning and guidance
Eichmann A. Regulation of blood vessel patterning and guidance. The FASEB Journal 2010, 24: 62.3-62.3. DOI: 10.1096/fasebj.24.1_supplement.62.3.Peer-Reviewed Original ResearchVertebrate embryonic developmentBlood vessel patterningLigand-receptor interactionsKey ligand-receptor interactionsVertebrate embryosVessel patterningZebrafish embryosPrimitive tubeGrowth factor gradientsEmbryonic developmentMesodermal cellsMajor axial vesselsMolecular mechanismsStereotyped architectureVascular developmentVascular systemSimilar branching patternsFactor gradientsCardinal veinEmbryosPrimitive vesselsBranched networkPattern formationEndothelial cellsHemodynamic forces
This site is protected by hCaptcha and its Privacy Policy and Terms of Service apply