2015
Paralytic Ileus in the Orthopaedic Patient
Daniels AH, Ritterman SA, Rubin LE. Paralytic Ileus in the Orthopaedic Patient. Journal Of The American Academy Of Orthopaedic Surgeons 2015, 23: 365-372. PMID: 25917235, DOI: 10.5435/jaaos-d-14-00162.Peer-Reviewed Original ResearchConceptsParalytic ileusMinor orthopaedic proceduresCommon adverse eventsProlonged hospital stayEarly patient mobilizationTreatment of ileusSevere patient morbidityMajor clinical concernAbdominal painBowel perforationHospital stayAdverse eventsBowel motilityHospital readmissionMultidisciplinary carePatient mobilizationTrauma patientsOrthopedic patientsPatient morbidityPharmacologic interventionsClinical signsSpinal surgeryIleusTraumatic injuryOrthopedic procedures
2014
A Phase II trial of Belinostat (PXD101) in patients with relapsed or refractory peripheral or cutaneous T‐cell lymphoma
Foss F, Advani R, Duvic M, Hymes KB, Intragumtornchai T, Lekhakula A, Shpilberg O, Lerner A, Belt RJ, Jacobsen ED, Laurent G, Ben‐Yehuda D, Beylot‐Barry M, Hillen U, Knoblauch P, Bhat G, Chawla S, Allen LF, Pohlman B. A Phase II trial of Belinostat (PXD101) in patients with relapsed or refractory peripheral or cutaneous T‐cell lymphoma. British Journal Of Haematology 2014, 168: 811-819. PMID: 25404094, DOI: 10.1111/bjh.13222.Peer-Reviewed Original ResearchMeSH KeywordsAdultAgedAged, 80 and overAntineoplastic AgentsDrug Administration ScheduleFemaleHistone Deacetylase InhibitorsHumansHydroxamic AcidsInfusions, IntravenousLymphoma, T-Cell, CutaneousLymphoma, T-Cell, PeripheralMaleMiddle AgedNeoplasm StagingRecurrenceSulfonamidesTreatment OutcomeYoung AdultConceptsCutaneous T-cell lymphomaPeripheral T-cell lymphomaObjective response rateT-cell lymphomaPrior systemic therapyStage IV diseaseSystemic therapyAdverse eventsTreatment-related serious adverse eventsRefractory peripheral T-cell lymphomaTreatment-related adverse eventsPan-histone deacetylase inhibitorInfusion site painSkin-directed therapiesGrade 4 thrombocytopeniaSerious adverse eventsPhase II trialJugular vein thrombosisAnti-angiogenic propertiesOpen labelII trialParalytic ileusPeripheral edemaPrimary endpointSite pain
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