2014
Pancreatic neuroendocrine tumors: Pathologic and molecular characteristics
Shi C, Klimstra D. Pancreatic neuroendocrine tumors: Pathologic and molecular characteristics. Seminars In Diagnostic Pathology 2014, 31: 498-511. PMID: 25441311, DOI: 10.1053/j.semdp.2014.08.008.Peer-Reviewed Original ResearchConceptsNeuroendocrine tumorsNeuroendocrine carcinomaWell-differentiated neuroendocrine tumorsPancreatic well-differentiated neuroendocrine tumorPancreatic neuroendocrine tumorsMolecular targeted therapyPancreatic neuroendocrine neoplasmsPancreatic neuroendocrine tumorigenesisNeuroendocrine neoplasmsNeuroendocrine tumorigenesisTumorPI3K/AKT/mTOR pathwayCarcinomaMolecular mechanismsChromatin remodelingNeoplasmsTP53TherapyPatients
2012
Unusual DNA mismatch repair–deficient tumors in Lynch syndrome: a report of new cases and review of the literature
Karamurzin Y, Zeng Z, Stadler Z, Zhang L, Ouansafi I, Al-Ahmadie H, Sempoux C, Saltz L, Soslow R, O'Reilly E, Paty P, Coit D, Shia J, Klimstra D. Unusual DNA mismatch repair–deficient tumors in Lynch syndrome: a report of new cases and review of the literature. Human Pathology 2012, 43: 1677-1687. PMID: 22516243, DOI: 10.1016/j.humpath.2011.12.012.Peer-Reviewed Original ResearchConceptsUnusual tumorRepair proteinsLynch syndromeMismatch repair proteinsPathogenic germ-line mutationsGerm-line mutationsWell-differentiated neuroendocrine tumorsPancreatic acinar cell carcinomaPancreatic well-differentiated neuroendocrine tumorAcinar cell carcinomaMicrosatellite instabilityDNA mismatch repair proteinsDetection of microsatellite instabilityPolymerase chain reaction detectionPolymerase chain reaction testMutation informationDNA mismatch repair deficient tumorsIdentification of tumorsMismatch repair-deficient tumorsMismatch repair genesNeuroendocrine tumorsAdrenocortical carcinomaAppendiceal carcinomaDetect Lynch syndromePeritoneal mesothelioma
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