2024
Navigating new norms: Addiction specialists' perspectives on opioid use disorder treatments and policy challenges in the fentanyl era
Weleff J, Christian N, Wang J, Singh M, De Aquino J, Saxon A, Vassallo G. Navigating new norms: Addiction specialists' perspectives on opioid use disorder treatments and policy challenges in the fentanyl era. American Journal On Addictions 2024, 34: 85-92. PMID: 39364597, PMCID: PMC11673400, DOI: 10.1111/ajad.13653.Peer-Reviewed Original ResearchSlow-release oral morphineOpioid use disorderBarriers to OUD treatmentAddiction specialistsOpioid use disorder managementUse disorderOUD treatmentThird-line monotherapyFisher's exact testOpioid use disorder treatmentOff-label prescribingOral morphineAgonist opioidsOpioid agonistsOpioid-related overdoseTherapeutic optionsWithdrawal symptomsNovel therapiesExact testOpioidMOUD prescribingSynthetic opioidsClinical practiceClinical approachCompare respondent characteristics
2020
Preoperative Gabapentin for Minimally Invasive Hysterectomy: A Randomized Controlled Trial
Huynh TQ, Patel NR, Goldstein ND, Makai GE. Preoperative Gabapentin for Minimally Invasive Hysterectomy: A Randomized Controlled Trial. Journal Of Minimally Invasive Gynecology 2020, 28: 237-244.e2. PMID: 32389735, DOI: 10.1016/j.jmig.2020.04.040.Peer-Reviewed Original ResearchMeSH KeywordsAcetaminophenAdultAgedAnalgesics, OpioidCelecoxibDouble-Blind MethodDrug Administration ScheduleDrug Therapy, CombinationEnhanced Recovery After SurgeryFemaleGabapentinHumansHysterectomyMiddle AgedMinimally Invasive Surgical ProceduresNarcoticsPain MeasurementPain, PostoperativePreoperative PeriodUterine DiseasesConceptsPreoperative gabapentinTotal narcoticsPain scoresInvasive hysterectomyStudy armsAcademic-affiliated community hospitalAdverse effectsOral morphineGabapentin usePreoperative regimenSecondary outcomesControlled TrialsPrimary outcomeBenign indicationsSingle doseSurgical detailsControl armCommunity hospitalGabapentinSurgeryControl groupDemographic characteristicsNarcoticsHysterectomyWomen
2019
Opioid tolerance impacts compliance with enhanced recovery pathway after major abdominal surgery
Owodunni O, Zaman M, Ighani M, Grant M, Bettick D, Sateri S, Magnuson T, Gearhart S. Opioid tolerance impacts compliance with enhanced recovery pathway after major abdominal surgery. Surgery 2019, 166: 1055-1060. PMID: 31526584, DOI: 10.1016/j.surg.2019.08.001.Peer-Reviewed Original ResearchConceptsEnhanced recovery pathwayMajor abdominal surgeryOpioid-tolerant patientsOpioid toleranceAbdominal surgeryLength of stayTolerant patientsRecovery pathwaysPostoperative outcomesMajor complicationsPathway complianceChallenging patient cohortNon-tolerant patientsPoor postoperative outcomesOperative Severity ScoreEnUmeration of MortalityRisk-adjusted analysisPrescribed opioid medicationsOutcomes of interestEvidence-based interventionsColorectal PhysiologicalOral morphineOpioid medicationsEmergency surgeryReadmission rates
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