2021
Fast-Degrading Tissue-Engineered Vascular Grafts Lead to Increased Extracellular Matrix Cross-Linking Enzyme Expression
Fukunishi T, Ong CS, He YJ, Inoue T, Zhang H, Steppan J, Matsushita H, Johnson J, Santhanam L, Hibino N. Fast-Degrading Tissue-Engineered Vascular Grafts Lead to Increased Extracellular Matrix Cross-Linking Enzyme Expression. Tissue Engineering Part A 2021, 27: 1368-1375. PMID: 33599167, DOI: 10.1089/ten.tea.2020.0266.Peer-Reviewed Original ResearchConceptsVascular stiffnessNative aortaVascular graftsTissue-engineered vascular graftsLysyl oxidaseTissue transglutaminaseECM remodeling processRisk of infectionExtracellular matrixArterial pressureAneurysmal formationCardiovascular diseaseInterposition conduitsGraftSynthetic vascular graftsVascular neotissue formationLOX expressionCross-linking enzymeMonthsRemodeling processLack of endothelializationArterial prosthesesEnzyme expressionCompliance mismatchAortaAortic remodeling and competitive flow after surgical treatment of aortic dissection
Chan SM, Brahmandam A, Cardella JA, Elefteriades J, Setaro JF, Mangi AA, Chaar C. Aortic remodeling and competitive flow after surgical treatment of aortic dissection. Journal Of Vascular Surgery Cases And Innovative Techniques 2021, 7: 404-407. PMID: 34278070, PMCID: PMC8261546, DOI: 10.1016/j.jvscit.2021.05.009.Peer-Reviewed Original ResearchAortic remodelingCompetitive flowAortic dissectionAcute lower extremity ischemiaExtra-anatomic conduitLower extremity ischemiaAxillobifemoral bypassExtremity ischemiaSurgical treatmentPatient outcomesVascular phenomenaNative aortaDissectionRemodelingPresent reportMalperfusionRecanalizationIschemiaThrombosisPatientsAortaReinstitutionBypass
2016
New Functional Tools for Antithrombogenic Activity Assessment of Live Surface Glycocalyx
Dimitrievska S, Gui L, Weyers A, Lin T, Cai C, Wu W, Tuggle CT, Sundaram S, Balestrini JL, Slattery D, Tchouta L, Kyriakides TR, Tarbell JM, Linhardt RJ, Niklason LE. New Functional Tools for Antithrombogenic Activity Assessment of Live Surface Glycocalyx. Arteriosclerosis Thrombosis And Vascular Biology 2016, 36: 1847-1853. PMID: 27386939, PMCID: PMC5283952, DOI: 10.1161/atvbaha.116.308023.Peer-Reviewed Original ResearchMeSH KeywordsAnimalsAntithrombinsAorta, ThoracicBiological AssayBlood CoagulationCells, CulturedChromatography, LiquidFactor XaGlycocalyxHeparinHeparitin SulfateHuman Umbilical Vein Endothelial CellsMaleMass SpectrometryMicroscopy, Electron, TransmissionRats, Sprague-DawleyReproducibility of ResultsThrombinTime FactorsConceptsHuman umbilical vein endothelial cellsUmbilical vein endothelial cellsVein endothelial cellsNative aortaEndothelial cellsHuman umbilical vein endothelial cell monolayersCultured human umbilical vein endothelial cellsFactor XaVascular healthEndothelial cell monolayersVascular diseaseRat aortaDamaged vasculatureAnticoagulant capacityVascular communityAortaTherapeutic developmentActivity assessmentCell monolayersVascular graftsLiquid chromatography-mass spectrometry analysisNovel assayGlycocalyxAssaysNative rat aorta
2005
αvβ3‐Targeted detection of arteriopathy in transplanted human coronary arteries: an autoradiographic study
Zhang J, Krassilnikova S, Gharaei AA, Fassaei HR, Esmailzadeh L, Asadi A, Edwards DS, Harris TD, Azure M, Tellides G, Sinusas AJ, Zaret BL, Bender JR, Sadeghi MM. αvβ3‐Targeted detection of arteriopathy in transplanted human coronary arteries: an autoradiographic study. The FASEB Journal 2005, 19: 1857-1859. PMID: 16150802, DOI: 10.1096/fj.05-4130fje.Peer-Reviewed Original ResearchMeSH KeywordsAnimalsAortaAutoradiographyCarotid Artery DiseasesCell MovementCell ProliferationCell TransplantationCells, CulturedChimeraCoronary VesselsDensitometryEndothelium, VascularHeart TransplantationHeterocyclic Compounds, 1-RingHumansImmunohistochemistryIntegrin alphaVbeta3Ki-67 AntigenLeukocytes, MononuclearMiceMice, SCIDMicroscopy, FluorescenceOrganometallic CompoundsRecombinant Fusion ProteinsTime FactorsTissue TransplantationUp-RegulationVascular DiseasesConceptsPeripheral blood mononuclear cellsGraft arteriopathyHuman coronary arteriesCoronary arteryAllogeneic human peripheral blood mononuclear cellsHuman/mouse chimeric modelAlphavbeta3 expressionHuman peripheral blood mononuclear cellsProliferative processesSevere combined immunodeficiency miceLate graft failureBlood mononuclear cellsCombined immunodeficiency miceAlphavbeta3 integrinSpecificity of uptakeCardiac transplantationConcentric narrowingGraft failureMononuclear cellsImmunodeficiency miceVascular remodelingNeointima formationNative aortaChimeric modelAutoradiographic study
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