2021
Fast-Degrading Tissue-Engineered Vascular Grafts Lead to Increased Extracellular Matrix Cross-Linking Enzyme Expression
Fukunishi T, Ong CS, He YJ, Inoue T, Zhang H, Steppan J, Matsushita H, Johnson J, Santhanam L, Hibino N. Fast-Degrading Tissue-Engineered Vascular Grafts Lead to Increased Extracellular Matrix Cross-Linking Enzyme Expression. Tissue Engineering Part A 2021, 27: 1368-1375. PMID: 33599167, DOI: 10.1089/ten.tea.2020.0266.Peer-Reviewed Original ResearchConceptsVascular stiffnessNative aortaVascular graftsTissue-engineered vascular graftsLysyl oxidaseTissue transglutaminaseECM remodeling processRisk of infectionExtracellular matrixArterial pressureAneurysmal formationCardiovascular diseaseInterposition conduitsGraftSynthetic vascular graftsVascular neotissue formationLOX expressionCross-linking enzymeMonthsRemodeling processLack of endothelializationArterial prosthesesEnzyme expressionCompliance mismatchAorta
2011
Age- and Gender-Dependency of Left Ventricular Geometry Assessed with Real-Time Three-Dimensional Transthoracic Echocardiography
Kaku K, Takeuchi M, Otani K, Sugeng L, Nakai H, Haruki N, Yoshitani H, Watanabe N, Yoshida K, Otsuji Y, Mor-Avi V, Lang R. Age- and Gender-Dependency of Left Ventricular Geometry Assessed with Real-Time Three-Dimensional Transthoracic Echocardiography. Journal Of The American Society Of Echocardiography 2011, 24: 541-547. PMID: 21345649, DOI: 10.1016/j.echo.2011.01.011.Peer-Reviewed Original ResearchConceptsLV mass/volume ratioLV volumesLeft ventricular geometryMass/volume ratioSphericity indexDevelopment of diastolic heart failureFull-volume data setsReal-time three-dimensional echocardiographyVentricular geometryValues of LV ejection fractionThree-dimensional transthoracic echocardiographyLeft ventricular (LVLV ejection fractionDiastolic heart failureThree-dimensional echocardiographyLoss of myocytesReal-time three-dimensional transthoracic echocardiographyGender-dependentLong-axis diameterTransthoracic echocardiographyEjection fractionLV massHeart failureHealthy subjectsVascular stiffness
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