2025
Ventricular ion channels and arrhythmias: an overview of physiology, pathophysiology and pharmacology
Liu S, Wang W, Yang Y, Huang Z. Ventricular ion channels and arrhythmias: an overview of physiology, pathophysiology and pharmacology. Medical Review 2025, 5: 231-243. PMID: 40600182, PMCID: PMC12207207, DOI: 10.1515/mr-2024-0085.Peer-Reviewed Original ResearchCardiac ion channelsAntiarrhythmic drugsIon channelsAssociated with inherited cardiac arrhythmiasAction potentialsVentricular ion channelsCardiac action potentialIon channel functionCardiac functionNa VChannel functionOverview of physiologyCardiac arrhythmiasDysfunctional mutationsGenetic mutationsArrhythmiasTherapeutic targetPropagation of cardiac action potentialsCardiac electrophysiologyCa VPathophysiologyCardiac healthDrugPharmacologyMutations
2024
Coupling of Slack and NaV1.6 sensitizes Slack to quinidine blockade and guides anti-seizure strategy development
Yuan T, Wang Y, Jin Y, Yang H, Xu S, Zhang H, Chen Q, Li N, Ma X, Song H, Peng C, Geng Z, Dong J, Duan G, Sun Q, Yang Y, Yang F, Huang Z. Coupling of Slack and NaV1.6 sensitizes Slack to quinidine blockade and guides anti-seizure strategy development. ELife 2024, 12 DOI: 10.7554/elife.87559.4.Peer-Reviewed Original Research
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