2016
Ipsilesional anodal tDCS enhances the functional benefits of rehabilitation in patients after stroke
Allman C, Amadi U, Winkler A, Wilkins L, Filippini N, Kischka U, Stagg C, Johansen-Berg H. Ipsilesional anodal tDCS enhances the functional benefits of rehabilitation in patients after stroke. Science Translational Medicine 2016, 8: 330re1. PMID: 27089207, PMCID: PMC5388180, DOI: 10.1126/scitranslmed.aad5651.Peer-Reviewed Original ResearchConceptsAnodal transcranial direct current stimulationTranscranial direct current stimulationAction Research Arm TestWolf Motor Function TestMagnetic resonance imagingMotor trainingPremotor cortexIpsilesional motorSham treatmentFunctional magnetic resonance imagingUpper extremity Fugl-Meyer scoreDaily motor trainingLong-term clinical outcomesAnodal tDCS groupFirst unilateral strokeDirect current stimulationIntervention-related increasesFugl-Meyer scoreSham treatment groupMotor Function TestMotor training programPrimary motor cortexStructural magnetic resonance imagingGray matter volumeMotor learning
2010
Skilled reaching training promotes astroglial changes and facilitated sensorimotor recovery after collagenase-induced intracerebral hemorrhage
Mestriner R, Pagnussat A, Boisserand L, Valentim L, Netto C. Skilled reaching training promotes astroglial changes and facilitated sensorimotor recovery after collagenase-induced intracerebral hemorrhage. Experimental Neurology 2010, 227: 53-61. PMID: 20850433, DOI: 10.1016/j.expneurol.2010.09.009.Peer-Reviewed Original ResearchConceptsIntracerebral hemorrhageSensorimotor cortexNo-taskCollagenase-induced intracerebral hemorrhageRehabilitation improves recoverySpontaneous intracerebral hemorrhageAssociated with functional improvementSensorimotor recoveryIntracerebral hemorrhage groupEffective interventionsMotor trainingDorsolateral striatumForelimb sensorimotor cortexIpsilateral striatumGFAP+ cellsBehavioral testsSham groupAstrocyte densityAstrocytic changesFunctional improvementHemorrhageAstroglial changesSkilled reachingLadder walkingCellular mechanismsCombination of NEP 1-40 Treatment and Motor Training Enhances Behavioral Recovery After a Focal Cortical Infarct in Rats
Fang PC, Barbay S, Plautz EJ, Hoover E, Strittmatter SM, Nudo RJ. Combination of NEP 1-40 Treatment and Motor Training Enhances Behavioral Recovery After a Focal Cortical Infarct in Rats. Stroke 2010, 41: 544-549. PMID: 20075346, PMCID: PMC2853474, DOI: 10.1161/strokeaha.109.572073.Peer-Reviewed Original ResearchConceptsMotor trainingWeeks postinfarctBehavioral recoverySkilled reachWeek 2Focal cortical infarctsFocal cortical ischemiaFocal ischemic infarctTreatment week 2Foot-fault testFocal ischemic injuryWeeks of treatmentSkilled reach taskNEP 1Cortical infarctsForelimb impairmentCortical ischemiaFoot faultsMotor recoveryIschemic infarctIschemic injuryMotor cortexEndothelin-1Intraventricular infusionMotor function
2000
Motor timing learned without motor training
Meegan D, Aslin R, Jacobs R. Motor timing learned without motor training. Nature Neuroscience 2000, 3: 860-862. PMID: 10966614, DOI: 10.1038/78757.Peer-Reviewed Original Research
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