Skilled reaching training promotes astroglial changes and facilitated sensorimotor recovery after collagenase-induced intracerebral hemorrhage
Mestriner R, Pagnussat A, Boisserand L, Valentim L, Netto C. Skilled reaching training promotes astroglial changes and facilitated sensorimotor recovery after collagenase-induced intracerebral hemorrhage. Experimental Neurology 2010, 227: 53-61. PMID: 20850433, DOI: 10.1016/j.expneurol.2010.09.009.Peer-Reviewed Original ResearchConceptsIntracerebral hemorrhageSensorimotor cortexNo-taskCollagenase-induced intracerebral hemorrhageRehabilitation improves recoverySpontaneous intracerebral hemorrhageAssociated with functional improvementSensorimotor recoveryIntracerebral hemorrhage groupEffective interventionsMotor trainingDorsolateral striatumForelimb sensorimotor cortexIpsilateral striatumGFAP+ cellsBehavioral testsSham groupAstrocyte densityAstrocytic changesFunctional improvementHemorrhageAstroglial changesSkilled reachingLadder walkingCellular mechanisms
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