2013
Impact of infarct-related artery patency before primary PCI on outcome in patients with ST-segment elevation myocardial infarction: the HORIZONS-AMI trial.
Rakowski T, Dudek D, Dziewierz A, Yu J, Witzenbichler B, Guagliumi G, Kornowski R, Hartmann F, Lansky AJ, Brener SJ, Mehran R, Stone GW. Impact of infarct-related artery patency before primary PCI on outcome in patients with ST-segment elevation myocardial infarction: the HORIZONS-AMI trial. EuroIntervention 2013, 8: 1307-14. PMID: 23538158, DOI: 10.4244/eijv8i11a199.Peer-Reviewed Original ResearchMeSH KeywordsAgedChi-Square DistributionCoronary AngiographyCoronary CirculationCoronary StenosisCoronary VesselsElectrocardiographyFemaleHumansKaplan-Meier EstimateMaleMiddle AgedMultivariate AnalysisMyocardial InfarctionPercutaneous Coronary InterventionPredictive Value of TestsProportional Hazards ModelsProspective StudiesRisk AssessmentRisk FactorsThrombosisTime FactorsTreatment OutcomeVascular PatencyConceptsEarly IRA patencyPrimary percutaneous coronary interventionPercutaneous coronary interventionHORIZONS-AMI trialOne-year mortalityIRA patencyIndependent predictorsST-segment elevation myocardial infarctionMyocardial blush grade 2Infarct-related artery patencyBaseline coronary angiographyBetter TIMI flowMyocardial Infarction 2Probable stent thrombosisTIMI 3 flowOne-year outcomesOutcomes of patientsElevation myocardial infarctionGood angiographic resultBaseline angiographyTIMI 0TIMI flowArtery patencyCoronary interventionCoronary angiography
2011
Predictors and Implications of Coronary Infarct Artery Patency at Initial Angiography in Patients With Acute Myocardial Infarction (from the CADILLAC and HORIZONS-AMI Trials)
Brener SJ, Mehran R, Brodie BR, Guagliumi G, Witzenbichler B, Cristea E, Xu K, Lansky AJ, Stone GW. Predictors and Implications of Coronary Infarct Artery Patency at Initial Angiography in Patients With Acute Myocardial Infarction (from the CADILLAC and HORIZONS-AMI Trials). The American Journal Of Cardiology 2011, 108: 918-923. PMID: 21764028, DOI: 10.1016/j.amjcard.2011.05.022.Peer-Reviewed Original ResearchMeSH KeywordsAbciximabAgedAngioplasty, Balloon, CoronaryAntibodies, MonoclonalCoronary AngiographyCoronary CirculationCoronary VesselsDrug-Eluting StentsElectrocardiographyFemaleFollow-Up StudiesHumansImmunoglobulin Fab FragmentsMaleMiddle AgedMyocardial InfarctionPlatelet Aggregation InhibitorsPredictive Value of TestsRegional Blood FlowVascular PatencyConceptsTIMI grade 3 flowGrade 3 flowFinal TIMI grade 3 flowST-segment elevation myocardial infarctionElevation myocardial infarctionIndependent predictorsMyocardial infarctionPre-percutaneous coronary intervention (PCI) thrombolysisMyocardial Infarction (TIMI) grade 3 flowAcute Myocardial Infarction trialExtensive coronary diseaseLate Angioplasty ComplicationsMyocardial Infarction trialInfarct artery patencyAcute myocardial infarctionSignificant independent predictorsHigh-risk characteristicsAngioplasty complicationsBaseline TIMIControlled AbciximabHarmonizing OutcomesInitial angiographyCause mortalityPrimary PCIArtery patency
2004
Prognostic utility of comparative methods for assessment of ST-segment resolution after primary angioplasty for acute myocardial infarction The controlled abciximab and device investigation to lower late angioplasty complications (CADILLAC) trial
McLaughlin M, Stone G, Aymong E, Gardner G, Mehran R, Lansky A, Grines C, Tcheng J, Cox D, Stuckey T, Garcia E, Guagliumi G, Turco M, Josephson M, Zimetbaum P. Prognostic utility of comparative methods for assessment of ST-segment resolution after primary angioplasty for acute myocardial infarction The controlled abciximab and device investigation to lower late angioplasty complications (CADILLAC) trial. Journal Of The American College Of Cardiology 2004, 44: 1215-1223. PMID: 15364322, DOI: 10.1016/j.jacc.2004.06.053.Peer-Reviewed Original ResearchMeSH KeywordsAgedAngioplasty, Balloon, CoronaryCoronary AngiographyCoronary CirculationElectrocardiographyFemaleHeart Conduction SystemHumansMaleMiddle AgedMultivariate AnalysisMyocardial InfarctionPostoperative ComplicationsPredictive Value of TestsPrognosisProspective StudiesRecurrenceRisk FactorsStatistics as TopicSurvival AnalysisTreatment OutcomeConceptsST-segment elevation resolutionPrimary percutaneous coronary interventionPrimary PCIST-segment elevationAcute myocardial infarctionLate Angioplasty Complications (CADILLAC) trialMaximum ST-segment elevationCombined end pointComplications TrialMyocardial infarctionBaseline ST-segment elevationEnd pointInfarct-related artery patencyHigh-risk categorizationPost-PCI electrocardiogramsST-segment resolutionPercutaneous coronary interventionTarget vessel patencyStrong independent predictorControlled AbciximabPrimary angioplastyArtery patencyCoronary interventionIndependent predictorsPrognostic utility
1996
Serial myocardial perfusion imaging with Tc-99m-labeled myocardial perfusion imaging agents in patients receiving thrombolytic therapy for acute myocardial infarction
Wackers F. Serial myocardial perfusion imaging with Tc-99m-labeled myocardial perfusion imaging agents in patients receiving thrombolytic therapy for acute myocardial infarction. Developments In Cardiovascular Medicine 1996, 173: 1-12. DOI: 10.1007/978-94-009-0115-5_1.Peer-Reviewed Original ResearchAcute myocardial infarctionThrombolytic therapyMyocardial infarctionInfarct arteryMyocardial perfusionRecurrent myocardial infarctionInfarct artery patencyLong-term mortalityAppropriate adjunctive therapyNovel treatment strategiesTerm mortalityAdjunctive therapyArtery patencyAcute infarctionHibernating myocardiumConventional therapyUnfavorable outcomeAntithrombotic agentsTreatment strategiesComparative efficacyReocclusionPatientsInfarctionTherapyBeneficial effects
1990
Thrombolytic therapy for myocardial infarction: Assessment of efficacy by myocardial perfusion imaging with technetium-99m sestamibi
Wackers F. Thrombolytic therapy for myocardial infarction: Assessment of efficacy by myocardial perfusion imaging with technetium-99m sestamibi. The American Journal Of Cardiology 1990, 66: e36-e41. PMID: 2145744, DOI: 10.1016/0002-9149(90)90610-d.Peer-Reviewed Original ResearchConceptsRecombinant tissue-type plasminogen activatorThrombolytic therapyMyocardial infarctionFirst acute myocardial infarctionInfarct-related artery patencyInitial risk areaPersistent coronary occlusionAcute chest painAcute myocardial infarctionAssessment of efficacyFuture clinical researchImaging agentNew thrombolytic agentsTissue-type plasminogen activatorArtery patencyChest painInfarct arterySuccessful thrombolysisConventional therapyCoronary occlusionHypoperfused myocardiumThrombolytic agentsMyocardial perfusionPatientsEnd point
1989
Serial quantitative planar technetium-99m isonitrile imaging in acute myocardial infarction: Efficacy for noninvasive assessment of thrombolytic therapy
Wackers F, Gibbons R, Verani M, Kayden D, Pellikka P, Behrenbeck T, Mahmarian J, Zaret B. Serial quantitative planar technetium-99m isonitrile imaging in acute myocardial infarction: Efficacy for noninvasive assessment of thrombolytic therapy. Journal Of The American College Of Cardiology 1989, 14: 861-873. PMID: 2507612, DOI: 10.1016/0735-1097(89)90456-7.Peer-Reviewed Original ResearchConceptsRecombinant tissue-type plasminogen activatorAcute myocardial infarctionPatent infarct-related arteryInfarct-related arteryThallium-201 imagingThrombolytic therapyMyocardial infarctionPlanar technetiumMyocardial perfusionExercise thallium-201 imagingFirst acute myocardial infarctionInfarct-related artery patencyInitial risk areaPersistent coronary occlusionSuccess of reperfusionMyocardial blood flowNew myocardial perfusionTissue-type plasminogen activatorArtery patencyChest painCoronary occlusionRepeat imagingBlood flowInfarctionThallium-201
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