2025
1109-P: Physician Referral Pathway to a Commercially Marketed Digital Exercise Resource for Type 1 Diabetes—Implementation Metrics from a Clinical Trial
ASH G, MAK S, (ELIAS) SPANAKIS I, LUKASIK J, NALLY L, FUCITO L, WEINZIMER S. 1109-P: Physician Referral Pathway to a Commercially Marketed Digital Exercise Resource for Type 1 Diabetes—Implementation Metrics from a Clinical Trial. Diabetes 2025, 74 DOI: 10.2337/db25-1109-p.Peer-Reviewed Original ResearchPrimary care providersHome-based exerciseExercise prescriptionReferral pathwaysParticipating primary care providersPCP responsesClinical trial participationExercise intensityCare providersTrials of participantsCoach appVigorous exerciseNon-HispanicEligible participantsPortal messagesClinical trials of participantsLatent autoimmune diabetes of adulthoodModerate exerciseHealthcare systemTrial participantsSnowball samplingExercisePain symptomsClinical trialsUncontrolled hypertension
2022
Effect of Structured, Moderate Exercise on Kidney Function Decline in Sedentary Older Adults
Shlipak M, Sheshadri A, Hsu F, Chen S, Jotwani V, Tranah G, Fielding R, Liu C, Ix J, Coca S, Pahor M, Guralnik J, Leeuwenburgh C, Caudle C, Crump L, Holmes L, Leeuwenburgh J, Lu C, Miller M, Espeland M, Ambrosius W, Applegate W, Beavers D, Byington R, Cook D, Furberg C, Harvin L, Henkin L, Hepler J, Hsu F, Lovato L, Roberson W, Rushing J, Rushing S, Stowe C, Walkup M, Hire D, Rejeski W, Katula J, Brubaker P, Mihalko S, Jennings J, Hadley E, Romashkan S, Patel K, Bonds D, McDermott M, Spring B, Hauser J, Kerwin D, Domanchuk K, Graff R, Rego A, Church T, Blair S, Myers V, Monce R, Britt N, Harris M, McGucken A, Rodarte R, Millet H, Tudor-Locke C, Butitta B, Donatto S, Cocreham S, King A, Castro C, Haskell W, Stafford R, Pruitt L, Berra K, Yank V, Fielding R, Nelson M, Folta S, Phillips E, Liu C, McDavitt E, Reid K, Kirn D, Pasha E, Kim W, Beard V, Tsiroyannis E, Hau C, Manini T, Anton S, Nayfield S, Buford T, Marsiske M, Sandesara B, Knaggs J, Lorow M, Marena W, Korytov I, Morris H, Fitch M, Singletary F, Causer J, Radcliff K, Newman A, Studenski S, Goodpaster B, Glynn N, Lopez O, Nadkarni N, Williams K, Newman M, Grove G, Bonk J, Rushing J, Kost P, Ives D, Kritchevsky S, Marsh A, Brinkley T, Demons J, Sink K, Kennedy K, Shertzer-Skinner R, Wrights A, Fries R, Barr D, Gill T, Axtell R, Kashaf S, de Rekeneire N, McGloin J, Wu K, Shepard D, Fennelly B, Iannone L, Mautner R, Sweeney Barnett T, Halpin S, Brennan M, Bugaj J, Zenoni M, Mignosa B, Williamson J, Hendrie H, Rapp S, Verghese J, Woolard N, Espeland M, Jennings J, Wilson V, Pepine C, Ariet M, Handberg E, Deluca D, Hill J, Szady A, Chupp G, Flynn G, Hankinson J, Vaz Fragoso C, Groessl E, Kaplan R. Effect of Structured, Moderate Exercise on Kidney Function Decline in Sedentary Older Adults. JAMA Internal Medicine 2022, 182: 650-659. PMID: 35499834, PMCID: PMC9062767, DOI: 10.1001/jamainternmed.2022.1449.Peer-Reviewed Original ResearchConceptsKidney function declineExercise interventionSedentary older adultsPhysical activityFunction declineOlder adultsClinical trialsHealth education control interventionModerate-intensity physical activityModerate-intensity exercise interventionAncillary analysisGlomerular filtration rateRandomized clinical trialsHigh physical activityModerate-intensity exerciseModerate-intensity activityCystatin C changesLifestyle interventionPrimary outcomeLarge trialsMean ageFiltration rateModerate exerciseOriginal trialMAIN OUTCOME
2005
Erythromelalgia: A hereditary pain syndrome enters the molecular era
Waxman SG, Dib‐Hajj S. Erythromelalgia: A hereditary pain syndrome enters the molecular era. Annals Of Neurology 2005, 57: 785-788. PMID: 15929046, DOI: 10.1002/ana.20511.Peer-Reviewed Reviews, Practice Guidelines, Standards, and Consensus StatementsConceptsPain syndromeGanglion neuronsCentral nervous system neuronsDorsal root ganglion neuronsChronic neuropathic painSodium channelsSympathetic ganglion neuronsIon channel mutationsChannel functionSodium channel functionAutosomal dominant disorderNeuropathic painPain disordersChronic painAltered excitabilityModerate exerciseSystem neuronsPrimary erythermalgiaRational therapyErythromelalgiaPainFirst human disorderModel diseaseWarm stimuliSyndrome
1987
An evaluation of respiratory effects following exposure to 2.0 ppm formaldehyde in asthmatics: lung function, symptoms, and airway reactivity.
Witek T, Schachter E, Tosun T, Beck G, Leaderer B. An evaluation of respiratory effects following exposure to 2.0 ppm formaldehyde in asthmatics: lung function, symptoms, and airway reactivity. Archives Of Environmental & Occupational Health 1987, 42: 230-7. PMID: 3310924.Peer-Reviewed Original ResearchConceptsMethacholine inhalation challenge testFlow-volume parametersInhalation challenge testSignificant airway obstructionAirway reactivityAirway obstructionAirway responsesAsthmatic volunteersLung functionSore throatAirway resistanceMethacholine concentrationModerate exerciseRespiratory effectsFormaldehyde exposurePpm exposureChallenge testSeparate daysEye irritationMedian decrementAsthmaticsSymptomsExposurePpm formaldehydeDegrees C
1986
A Study of Respiratory Effects from Exposure to 2 ppm Formaldehyde in Healthy Subjects
Schachter E, Witek T, Tosun T, Leaderer B, Beck G. A Study of Respiratory Effects from Exposure to 2 ppm Formaldehyde in Healthy Subjects. Archives Of Environmental & Occupational Health 1986, 41: 229-239. PMID: 3767432, DOI: 10.1080/00039896.1986.9938338.Peer-Reviewed Original ResearchConceptsHealthy subjectsUpper airwaySeparate daysMaximal flow-volume curvesLower airway symptomsFlow-volume curvesAirway responsesAirway symptomsPulmonary functionRespiratory symptomsSignificant bronchoconstrictionLung functionSymptom diaryAirway resistanceIrritative phenomenaModerate exercisePhysiologic alterationsRespiratory effectsSubjective complaintsBaseline responsivenessFA exposureHealthy individualsIrritative propertiesRespiratory systemSuch exposure
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