2023
The Immune Checkpoint Siglec-15 in Promoting Immune Dysregulation in Non-Hodgkin's Lymphomas
Francis D, Dougan J, Pillsbury C, Park S, Langermann S, Koff J, Li Z, Flowers C, Porter C. The Immune Checkpoint Siglec-15 in Promoting Immune Dysregulation in Non-Hodgkin's Lymphomas. Blood 2023, 142: 4367. DOI: 10.1182/blood-2023-190405.Peer-Reviewed Original ResearchDiffuse large B-cell lymphomaB-cell lymphomaAggressive B-cell lymphomasGerminal center B cellsImmune responseBurkitt's lymphomaLymphoma casesDisease progressionSiglec-15Immune deficient (SCID) BALB/c miceR diffuse large B-cell lymphomaB cellsDeficient BALB/c miceLocal anti-tumour immune responseAggressive mature B-cell lymphomaAnti-tumor immune responseBALB/c miceLarge B-cell lymphomaHealthy donor PBMCsIntensive salvage regimensMost diffuse large B-cell lymphomasEvent-free survivalFirst-line treatmentRefractory hematologic malignanciesNon-Hodgkin lymphoma cases
2022
Evaluating information loss in the National Cancer Database from cases lost to follow‐up
Cotler JH, Nogueira L, McCabe R, Nelson H, Brajcich BC, Boffa DJ, Lum SS, Harris JB, Hawhee V, Mullett TW, Bilimoria KY, Palis BE. Evaluating information loss in the National Cancer Database from cases lost to follow‐up. Journal Of Surgical Oncology 2022, 126: 1123-1132. PMID: 36029288, DOI: 10.1002/jso.26977.Peer-Reviewed Original ResearchConceptsNational Cancer DatabaseCancer casesPediatric casesAdult casesCancer DatabaseRectal cancer casesLung cancer casesMean survival timeBreast cancer casesHazard ratioCancer RegistryYears postdiagnosisSurvival outcomesLymphoma casesSurvival timeLeukemia casesSurvival analysisResource burdenFollowTotalMinimal differencesYearsAnnual increasePostdiagnosisPatientsUtility of liquid biopsy (LB)-based comprehensive genomic profiling (CGP) of circulating tumor DNA (ctDNA) in lymphomas and plasma cell neoplasms.
Mata D, Shanmugam V, Decker B, Schrock A, Tukachinsky H, Williams E, Ross J, Montesion M, Oxnard G, Vergilio J, Xu M, Benhamida J. Utility of liquid biopsy (LB)-based comprehensive genomic profiling (CGP) of circulating tumor DNA (ctDNA) in lymphomas and plasma cell neoplasms. Journal Of Clinical Oncology 2022, 40: e19543-e19543. DOI: 10.1200/jco.2022.40.16_suppl.e19543.Peer-Reviewed Original ResearchDiffuse large B-cell lymphomaComprehensive genomic profilingNon-Hodgkin lymphomaPlasma cell neoplasmsPathogenic alterationsCell neoplasmsHybrid-capture next-generation sequencingLarge B-cell lymphomaRoutine clinical careActionable genomic alterationsGenomic alterationsHodgkin's lymphoma casesTumor biopsy specimensB-cell lymphomaPathogenic genomic alterationsUnique patient samplesRetrospective studyBiopsy specimensClinical careLymphoma casesTissue biopsiesLymphomaInsufficient tumorTumor DNAGenomic profiling
2018
Disparities by race, age, and sex in the improvement of survival for lymphoma: Findings from a population-based study
Mukhtar F, Boffetta P, Dabo B, Park JY, Tran CTD, Tran TV, Tran HT, Whitney M, Risch HA, Le LC, Zheng W, Shu XO, Luu HN. Disparities by race, age, and sex in the improvement of survival for lymphoma: Findings from a population-based study. PLOS ONE 2018, 13: e0199745. PMID: 29995909, PMCID: PMC6040734, DOI: 10.1371/journal.pone.0199745.Peer-Reviewed Original ResearchConceptsLymphoma patientsHodgkin's lymphomaAge groupsHazard ratioDisease-specific mortalityFive-year survivalHodgkin's lymphoma patientsImprovement of survivalPopulation-based studyProportional hazards regressionConfidence intervalsCause-specific mortalityIncident lymphoma casesSEER cancer registryYears of ageOlder age groupsPatients 20Surveillance EpidemiologyCancer RegistrySurvival improvementHazards regressionLymphoma casesNHL survivalPatientsLymphoma
2004
Flow Cytometric DNA Ploidy Analysis of Peripheral Blood From Patients With Sézary Syndrome
Wang, Li N, Heald P, Fisk JM, Fadare O, Howe JG, McNiff JM, Smith BR. Flow Cytometric DNA Ploidy Analysis of Peripheral Blood From Patients With Sézary Syndrome. American Journal Of Clinical Pathology 2004, 122: 774-782. PMID: 15491974, DOI: 10.1309/8b849fc6phap8fdd.Peer-Reviewed Original ResearchConceptsDNA ploidy studiesNeoplastic T cellsSezary syndromeMinimal residual diseasePloidy studiesResidual diseaseBlood-based diagnosisT cellsBlood samplesCutaneous T-cell lymphoma casesT-cell lymphoma casesCytometric DNA ploidy analysisBlood tumor burdenPeripheral blood samplesLarge cell transformationLow-grade groupDNA ploidy analysisAneuploid cellsSézary syndromeLymph nodesImmunophenotypic findingsTumor burdenPeripheral bloodLymphoma casesAneuploid group
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