2021
White Matter Hyperintensity and Cardiovascular Disease Outcomes in the SPRINT MIND Trial
Sheibani N, Wong KH, Turan TN, Yeatts SD, Gottesman RF, Prabhakaran S, Rost NS, de Havenon A. White Matter Hyperintensity and Cardiovascular Disease Outcomes in the SPRINT MIND Trial. Journal Of Stroke And Cerebrovascular Diseases 2021, 30: 105764. PMID: 33823461, PMCID: PMC8107132, DOI: 10.1016/j.jstrokecerebrovasdis.2021.105764.Peer-Reviewed Original ResearchConceptsSystolic Blood Pressure Intervention TrialWhite matter hyperintensity volumeSystolic blood pressurePrimary outcomeHazard ratioLog-transformed white matter hyperintensity volumeGoal systolic blood pressureLog-transformed continuous variableComposite of strokeIntensive BP loweringHigh cardiovascular riskAcute coronary syndromeCongestive heart failureProspective clinical trialsCardiovascular disease outcomesFuture CVD riskWhite matter hyperintensitiesSubset of participantsBP loweringCardiovascular deathCardiovascular eventsCoronary syndromeCardiovascular riskCVD riskBlood pressure
2010
Depression Predicts Elevated Endothelin-1 in Patients With Coronary Artery Disease
Burg MM, Martens EJ, Collins D, Soufer R. Depression Predicts Elevated Endothelin-1 in Patients With Coronary Artery Disease. Biopsychosocial Science And Medicine 2010, 73: 2-6. PMID: 20947777, PMCID: PMC3016462, DOI: 10.1097/psy.0b013e3181fdfb25.Peer-Reviewed Original ResearchConceptsCoronary artery diseaseEndothelin-1Beck Depression InventoryBDI scoresLogistic regression modelsArtery diseaseLog-transformed continuous variableRisk thresholdElevated endothelin-1ET-1 elevationET-1 levelsEvent-free survivalMorning blood samplesWorse depression symptomsDepression symptom severityEarly morbidityRegression modelsPoor survivalPlaque ruptureAdjusted modelBlood samplesDepressive symptomsDepression severityDepression symptomsDepression Inventory
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