2022
Pharmacokinetics and Tolerability of Intraperitoneal Chloroprocaine After Fetal Extraction in Women Undergoing Cesarean Delivery
Togioka BM, Zarnegarnia Y, Bleyle LA, Koop D, Brookfield K, Yanez ND, Treggiari MM. Pharmacokinetics and Tolerability of Intraperitoneal Chloroprocaine After Fetal Extraction in Women Undergoing Cesarean Delivery. Anesthesia & Analgesia 2022, 135: 777-786. PMID: 35544759, DOI: 10.1213/ane.0000000000006064.Peer-Reviewed Original ResearchConceptsLocal anesthetic systemic toxicityPeak plasma concentrationCesarean deliveryPlasma concentrationsSystemic toxicityIntraperitoneal administrationFetal extractionMultiple-dose escalation studyPatient drug exposureMaternal blood samplesMaximum plasma concentrationRoute of administrationYears of ageClinical tolerabilityEscalation studySpinal anesthesiaUterine closureNeuraxial anesthesiaClinical symptomsDrug exposureClinical signsWomen 18Prospective assessmentBlood samplesPharmacokinetic profile
2021
Ultrasound Guided Brachial Plexus Block
Li J, Sharma A, Credaroli E, Vadivelu N, Liu H. Ultrasound Guided Brachial Plexus Block. 2021, 121-128. DOI: 10.1007/978-3-030-46839-2_13.ChaptersLocal anesthetic systemic toxicityReal-time ultrasound guidanceFaster block onsetBrachial plexus blockBrachial plexus blockadeUpper extremity blocksEntire upper extremityUpper extremity proceduresOpioid reductionOpioid sparingBlock successExcellent analgesiaPlexus blockPlexus blockadeCervical plexusNerve stimulationGeneral anesthesiaBrachial plexusExtremity proceduresUpper extremityRegional anesthesiaSurgical anesthesiaIntravascular injectionUltrasound guidanceLandmark technique
2020
Anesthesia for Obstetric Disasters
Fardelmann KL, Alian AA. Anesthesia for Obstetric Disasters. Advances In Anesthesia 2020, 38: 229-250. PMID: 34106836, DOI: 10.1016/j.aan.2020.09.001.ChaptersConceptsLocal anesthetic systemic toxicityDifficult obstetric airwayAmniotic fluid embolismMaternal cardiac arrestAnesthesia complicationsObstetric airwayObstetric disasterFetal morbidityFetal outcomesHELLP syndromeHypertensive disordersCardiac arrestMaternal mortalityNeuraxial blockadeObstetric anesthesiologistObstetric emergenciesLive birthsSystemic toxicityExpeditious interventionMortalityMorbidityEmbolismComplicationsHemorrhageAirwayAnesthesia for Obstetric Disasters
Fardelmann KL, Alian AA. Anesthesia for Obstetric Disasters. Anesthesiology Clinics 2020, 38: 85-105. PMID: 32008659, DOI: 10.1016/j.anclin.2019.10.005.ChaptersConceptsLocal anesthetic systemic toxicityDifficult obstetric airwayAmniotic fluid embolismMaternal cardiac arrestAnesthesia complicationsObstetric airwayObstetric disasterFetal morbidityFetal outcomesHELLP syndromeHypertensive disordersCardiac arrestMaternal mortalityNeuraxial blockadeObstetric anesthesiologistObstetric emergenciesLive birthsSystemic toxicityExpeditious interventionMortalityMorbidityEmbolismComplicationsHemorrhageAirway
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