2008
Duration of Intrapartum Prophylaxis and Concentration of Penicillin G in Fetal Serum at Delivery
Barber EL, Zhao G, Buhimschi IA, Illuzzi JL. Duration of Intrapartum Prophylaxis and Concentration of Penicillin G in Fetal Serum at Delivery. Obstetrics And Gynecology 2008, 112: 265-270. PMID: 18669721, PMCID: PMC3144749, DOI: 10.1097/aog.0b013e31817d0246.Peer-Reviewed Original ResearchConceptsHours of prophylaxisMinimal inhibitory concentrationEarly-onset group B streptococcus sepsisPenicillin GGroup B streptococcus sepsisMaternal body mass indexUmbilical cord blood samplesMultivariable linear regression analysisGBS-positive womenIntravenous penicillin GDuration of prophylaxisProspective cohort studyBody mass indexCord blood samplesNumber of dosesDuration of exposureGBS sepsisIntrapartum prophylaxisMaintenance dosingPrecipitous laborStreptococcus sepsisLast doseSingleton gestationsCohort studyMass index
1987
Treatment of Lyme disease
Steere A, Green J, Hutchinson G, Rahn D, Pachner A, Schoen R, Sigal L, Taylor E, Malawista S. Treatment of Lyme disease. International Journal Of Medical Microbiology 1987, 263: 352-356. PMID: 3109144, DOI: 10.1016/s0176-6724(87)80092-5.Peer-Reviewed Original ResearchConceptsPenicillin-treated patientsLyme diseaseHigh-dose intravenous penicillinAttacks of arthritisIntravenous penicillin GHalf of patientsMajor late complicationsEarly Lyme diseaseIntramuscular benzathine penicillinIntravenous penicillinLate complicationsAntibiotic therapyArthritis patientsBenzathine penicillinMotor deficitsNeurologic abnormalitiesLate diseaseLate symptomsPatientsPhenoxymethyl penicillinAntibiotic agentsComplete recoveryDiseasePenicillin GArthritis
1985
Successful Parenteral Penicillin Therapy of Established Lyme Arthritis
Steere A, Green J, Schoen R, Taylor E, Hutchinson G, Rahn D, Malawista S. Successful Parenteral Penicillin Therapy of Established Lyme Arthritis. New England Journal Of Medicine 1985, 312: 869-874. PMID: 3883177, DOI: 10.1056/nejm198504043121401.Peer-Reviewed Original ResearchConceptsLyme arthritisComplete resolutionDouble-blind placebo-controlled trialAttacks of arthritisIntravenous penicillin GParenteral penicillin therapyPlacebo-controlled trialPenicillin-treated patientsErythema chronicum migransMean followPenicillin therapyParenteral therapyParenteral penicillinIntraarticular corticosteroidsJoint fluidArthritisPatientsLyme spirocheteFurther experienceTherapyPenicillin GOptimal courseDaysCorticosteroidsPlacebo
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