2025
T cells of patients with systemic sclerosis or Sjögren’s disease display an aberrant metabolic state and memory phenotype in blood and lungs
Ehlers C, Biermann H, Thiele T, Schupp J, Villa M, Jänke C, Risser L, Witte T, Kalinke U, Seeliger B, Graalmann T. T cells of patients with systemic sclerosis or Sjögren’s disease display an aberrant metabolic state and memory phenotype in blood and lungs. Rheumatology 2025, 64: 4806-4815. PMID: 40244816, DOI: 10.1093/rheumatology/keaf198.Peer-Reviewed Original ResearchInterstitial lung diseaseCD8+ T cellsT cells of patientsBronchoalveolar lavage of patientsSystemic sclerosisBronchoalveolar lavageT cellsSjogren's diseaseHealthy controlsBlood CD8+ T cellsBlood T cells of patientsLevels of HLA-DRIncreased expression of CD25Involvement of T cellsExpression of CD25Increased CD4+T cell responsesT cell receptor engagementLungs of patientsT cell characterizationExpressed increased levelsCell type 2Aberrant metabolic stateExpressed significant levelsSpectral flow cytometry
2016
Pathogenesis of minimal change nephrotic syndrome: an immunological concept
Kim S, Park J, Han K, Kronbichler A, Saleem M, Oh J, Lim B, Shin J. Pathogenesis of minimal change nephrotic syndrome: an immunological concept. Clinical And Experimental Pediatrics 2016, 59: 205-211. PMID: 27279884, PMCID: PMC4897155, DOI: 10.3345/kjp.2016.59.5.205.Peer-Reviewed Original ResearchMinimal change nephrotic syndromePathogenesis of MCNSIdiopathic nephrotic syndromeT cellsNephrotic syndromeB cellsAdult minimal change nephrotic syndromeInvolvement of T cellsInduction of CD80T-cell disordersRegulatory T cellsB cell biologyImpaired autoregulatory functionTreatment of childhoodGlomerular filtration barrierTherapeutic responseMassive proteinuriaCirculating factorsSyndromeImmunological conceptsPathogenesisFiltration barrierIncreased levelsAutoregulatory functionChildren
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