2025
Reliability of Central Vein Sign Imaging With 3T FLAIR* in a Multicenter Study
Martin M, Cao Q, Luskin E, Renner B, Daboul L, O'Donnell C, Rodrigues P, Derbyshire J, Azevedo C, Bar‐Or A, Caverzasi E, Calabresi P, Cree B, Freeman L, Henry R, Longbrake E, Oh J, Papinutto N, Pelletier D, Prchkovska V, Ramos M, Samudralwar R, Schindler M, Sotirchos E, Sicotte N, Solomon A, Reich D, Ontaneda D, Shinohara R, Sati P. Reliability of Central Vein Sign Imaging With 3T FLAIR* in a Multicenter Study. Journal Of Neuroimaging 2025, 35: e70011. PMID: 39838609, DOI: 10.1111/jon.70011.Peer-Reviewed Original ResearchConceptsCentral vein signMulticenter studyMultiple sclerosisT2-weighted fluid-attenuated inversion recoveryClinical settingMRI vendorsFluid-attenuated inversion recoveryDiagnosis of MSPost-GdContrast-to-noise ratioGd-based contrast agentsNo significant differenceT2*-weightedImaging sitesDiagnostic imaging biomarkersImaging biomarkersInversion recoverySignificant differenceMRIFLAIRContrast agents
2024
Multicenter Automated Central Vein Sign Detection Performs as Well as Manual Assessment for the Diagnosis of Multiple Sclerosis.
Manning A, Letchuman V, Martin M, Gombos E, Robert-Fitzgerald T, Cao Q, Raza P, O'Donnell C, Renner B, Daboul L, Rodrigues P, Ramos M, Derbyshire J, Azevedo C, Bar-Or A, Caverzasi E, Calabresi P, Cree B, Freeman L, Henry R, Longbrake E, Oh J, Papinutto N, Pelletier D, Samudralwar R, Suthiphosuwan S, Schindler M, Bilello M, Song J, Sotirchos E, Sicotte N, Al-Louzi O, Solomon A, Reich D, Ontaneda D, Sati P, Shinohara R. Multicenter Automated Central Vein Sign Detection Performs as Well as Manual Assessment for the Diagnosis of Multiple Sclerosis. American Journal Of Neuroradiology 2024, 46: 620-626. PMID: 39332906, PMCID: PMC11979820, DOI: 10.3174/ajnr.a8510.Peer-Reviewed Original ResearchCentral vein signCVS+ lesionsWhite matter lesionsMultiple sclerosisMulticenter studyProportions of white matter lesionsSuspicion of MSReceiver-operating characteristic curveFluid-attenuated inversion recoveryDiagnosis of multiple sclerosisDiagnosis of MSMagnetic resonance imagingAtypical clinical syndromeRadiological mimicsClinical syndromeDiagnostic imaging biomarkersManual assessmentT MRIClinical implementationImaging biomarkersLesionsInversion recoveryResonance imagingCharacteristic curveInter-rater reliability
2022
Portable, low-field magnetic resonance imaging enables highly accessible and dynamic bedside evaluation of ischemic stroke
Yuen MM, Prabhat AM, Mazurek MH, Chavva IR, Crawford A, Cahn BA, Beekman R, Kim JA, Gobeske KT, Petersen NH, Falcone GJ, Gilmore EJ, Hwang DY, Jasne AS, Amin H, Sharma R, Matouk C, Ward A, Schindler J, Sansing L, de Havenon A, Aydin A, Wira C, Sze G, Rosen MS, Kimberly WT, Sheth KN. Portable, low-field magnetic resonance imaging enables highly accessible and dynamic bedside evaluation of ischemic stroke. Science Advances 2022, 8: eabm3952. PMID: 35442729, PMCID: PMC9020661, DOI: 10.1126/sciadv.abm3952.Peer-Reviewed Original ResearchIschemic strokeMagnetic resonance imagingResonance imagingFluid-attenuated inversion recoveryDiffusion-weighted imaging sequencesStroke volume measurementsStroke pathwayStroke severityFunctional outcomeLow-field magnetic resonance imagingBedside evaluationClinical managementStroke volumeMRI studiesStrokePatientsBrain imagingCerebellar structuresHigh-field MRI studiesHyperintense regionsInversion recoveryInfarctsUseful imagingVolume measurements
2021
Correlation of LET With MRI Changes in Brain and Potential Implications for Normal Tissue Complication Probability for Patients With Meningioma Treated With Pencil Beam Scanning Proton Therapy
Bertolet A, Abolfath R, Carlson DJ, Lustig RA, Hill-Kayser C, Alonso-Basanta M, Carabe A. Correlation of LET With MRI Changes in Brain and Potential Implications for Normal Tissue Complication Probability for Patients With Meningioma Treated With Pencil Beam Scanning Proton Therapy. International Journal Of Radiation Oncology • Biology • Physics 2021, 112: 237-246. PMID: 34425196, DOI: 10.1016/j.ijrobp.2021.08.027.Peer-Reviewed Original ResearchConceptsT2/fluidNormal tissue complication probabilityComplication probabilityCohort of patientsGroup of patientsPencil beam scanning proton therapyPlanning computed tomography (CT) imagesMost patientsMRI changesProton radiation therapySame doseRadiation therapyHigh doseLow dosePatientsBrain normal tissuesSuperficial lesionsHigh linear energy transferNormal tissuesMagnetic resonance imagesComputed tomography imagesDoseMeningiomasInversion recoveryTherapy
2016
Comparison of stroke volume evolution on diffusion-weighted imaging and fluid-attenuated inversion recovery following endovascular thrombectomy
Federau C, Christensen S, Mlynash M, Tsai J, Kim S, Zaharchuk G, Inoue M, Straka M, Mishra NK, Kemp S, Lansberg MG, Albers GW. Comparison of stroke volume evolution on diffusion-weighted imaging and fluid-attenuated inversion recovery following endovascular thrombectomy. International Journal Of Stroke 2016, 12: 510-518. PMID: 27811306, DOI: 10.1177/1747493016677985.Peer-Reviewed Original ResearchConceptsInfarct lesion volumeFluid-attenuated inversion recoveryDiffusion-weighted imagingLesion volumeEndovascular thrombectomyInversion recoveryDay 5Fluid-attenuated inversion recovery lesionsPost-stroke onsetDegree of reperfusionStroke lesion volumeFluid-attenuated inversion recovery imagesInversion recovery imagesInfarct volumeInfarct growthStroke onsetSymptom onsetLesion growthPatientsRecovery imagesInterquartile rangeThrombectomyProcedure images
2010
Imaging Cortical Lesions in Multiple Sclerosis With Ultra–High-Field Magnetic Resonance Imaging
Pitt D, Boster A, Pei W, Wohleb E, Jasne A, Zachariah CR, Rammohan K, Knopp MV, Schmalbrock P. Imaging Cortical Lesions in Multiple Sclerosis With Ultra–High-Field Magnetic Resonance Imaging. JAMA Neurology 2010, 67: 812-818. PMID: 20625086, DOI: 10.1001/archneurol.2010.148.Peer-Reviewed Original ResearchConceptsCortical lesion detectionCortical lesionsMultiple sclerosisLesion typeCortical multiple sclerosis lesionsBrain tissueCortical lesion typesMultiple sclerosis tissueAutopsied brain tissueInversion recoveryMagnetic resonance imagingMultiple sclerosis lesionsCorresponding histological sectionsLesion detectionMyelin basic proteinHypointense ringUndetected lesionsImmunohistochemical analysisSclerosis lesionsLesionsResonance imagingSensitivity of T2SclerosisMagnetic resonance imagesLesion visibility
1997
Homocarnosine and the measurement of neuronal pH in patients with epilepsy
Rothman D, Behar K, Prichard J, Petroff O. Homocarnosine and the measurement of neuronal pH in patients with epilepsy. Magnetic Resonance In Medicine 1997, 38: 924-929. PMID: 9402193, DOI: 10.1002/mrm.1910380611.Peer-Reviewed Original Research
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