2024
Circulating Metabolite Profiles and Risk of Coronary Heart Disease Among Racially and Geographically Diverse Populations
Deng K, Gupta D, Shu X, Lipworth L, Zheng W, Cai H, Cai Q, Yu D. Circulating Metabolite Profiles and Risk of Coronary Heart Disease Among Racially and Geographically Diverse Populations. Circulation Genomic And Precision Medicine 2024, 17: e004437. PMID: 38950084, PMCID: PMC11335450, DOI: 10.1161/circgen.123.004437.Peer-Reviewed Original ResearchConceptsMetabolite risk scoreConventional risk factorsCoronary heart diseaseConditional logistic regressionRisk factorsIncident coronary heart diseaseCirculating metabolitesC-indexAssociated with incident coronary heart diseaseCHD casesHeart diseaseCirculating metabolite profilesFollow-up durationBaseline plasma samplesIncident CHD casesLogistic regressionBody mass indexRisk of coronary heart diseaseAssociated with CHD riskCase-control pairsImprove CHD risk predictionGeographically diverse populationsUntargeted metabolomicsRisk predictionFamily history
2007
Metabolic syndrome, its preeminent clusters, incident coronary heart disease and all‐cause mortality – results of prospective analysis for the Atherosclerosis Risk in Communities study
Hong Y, Jin X, Mo J, Lin H, Duan Y, Pu M, Wolbrette D, Liao D. Metabolic syndrome, its preeminent clusters, incident coronary heart disease and all‐cause mortality – results of prospective analysis for the Atherosclerosis Risk in Communities study. Journal Of Internal Medicine 2007, 262: 113-122. PMID: 17598819, DOI: 10.1111/j.1365-2796.2007.01781.x.Peer-Reviewed Original ResearchConceptsCoronary heart diseaseIncident CHD casesAll-Cause MortalityMetS componentsAtherosclerosis RiskElevated BPLow HDL-C groupHDL-C groupRelative riskClustering of MetS componentsIncident coronary heart diseaseCommunity studiesFatal coronary heart diseaseHospitalized myocardial infarctionPrevention of coronary heart diseaseConfidence intervalsCHD casesBi-racial cohortIncidence of coronary heart diseaseATP III criteriaIncreased waist circumferenceMetabolic syndromeMiddle-aged AmericansHDL-CLow HDL-C
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