2006
BRIT1/MCPH1: A Guardian of Genome and an Enemy of Tumors
Chaplet M, Rai R, Jackson-Bernitsas D, Li K, Lin SY. BRIT1/MCPH1: A Guardian of Genome and an Enemy of Tumors. Cell Cycle 2006, 5: 2579-2583. PMID: 17172830, DOI: 10.4161/cc.5.22.3471.Peer-Reviewed Original ResearchConceptsDNA damageTiming of mitosisDNA damage checkpointDNA damage responseCell cycle checkpointsGuardian of genomePotential tumor suppressorDamage checkpointEukaryotic cellsIntriguing proteinNuclear fociGenomic stabilityDamage responseCycle checkpointsBRIT1Damage sensorTumor suppressorCellular responsesSophisticated mechanismsCancer initiationCentrosomal abnormalitiesNeoplastic transformationGenomeProteinImportant molecules
2001
Genetics of Central Nervous System Developmental Disorders
Naegele J, Lombroso P. Genetics of Central Nervous System Developmental Disorders. Child And Adolescent Psychiatric Clinics Of North America 2001, 10: 225-239. PMID: 11351796, DOI: 10.1016/s1056-4993(18)30055-5.Peer-Reviewed Original Research
1988
Proteolytic processing of human brain alpha spectrin (fodrin): identification of a hypersensitive site
Harris A, Morrow J. Proteolytic processing of human brain alpha spectrin (fodrin): identification of a hypersensitive site. Journal Of Neuroscience 1988, 8: 2640-2651. PMID: 3074159, PMCID: PMC6569499, DOI: 10.1523/jneurosci.08-07-02640.1988.Peer-Reviewed Original ResearchConceptsLong-term potentiationBrain spectrinCalcium-dependent mechanismCalcium-dependent neutral proteaseCalcium-dependent proteaseCentral molecular mechanismsSite of actionReceptor functionPostsynaptic membraneCalcium-dependent mannerFurther investigationMolecular mechanismsGel overlay techniqueAlpha subunitNeutral proteaseNonerythroid spectrinImportant moleculesProteolytic processingCleavage fragmentsPotentiationProtease
1986
Proton NMR Studies of RNA’S and Related Enzymes Using Isotope Labels
Redfield A, Choi B, Griffey R, Jarema M, Rosevear P, Hoben P, Swanson R, Soll D. Proton NMR Studies of RNA’S and Related Enzymes Using Isotope Labels. NATO Science Series A: 1986, 99-112. DOI: 10.1007/978-1-4684-5173-3_9.Peer-Reviewed Original ResearchTransfer RNATRNA synthetasesProton NMRAminoacyl-tRNA synthetasesSmall RNA fragmentsDetails of recognitionProton NMR studiesNitrogen-15 labellingSmall proteinsTRNARNA fragmentsSmall enzymeNMR methodologyRelated enzymesNMR studiesRNANMRSmall moleculesLarge moleculesIsotope labelsSynthetasesImportant moleculesEnzymeNucleic acidsMolecules
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