2022
2017 – HUMAN HEMATOPOIETIC STEM CELL ONTOGENY ACROSS DEVELOPMENT AND MATURATION
Rowe G, Li H, Cote P, Kuoch M, Ezike J, Afanassiev A, Greenstreet L, Tarantino G, Zhang S, Whangbo J, Butty V, Moiso E, Falchetti M, Connelly G, Morris V, Wang D, Chen A, Bianchi G, Daley G, Garg S, Liu D, Chou S, Regev A, da Rocha E, Schiebinger G. 2017 – HUMAN HEMATOPOIETIC STEM CELL ONTOGENY ACROSS DEVELOPMENT AND MATURATION. Experimental Hematology 2022, 111: s39-s40. DOI: 10.1016/j.exphem.2022.07.049.Peer-Reviewed Original ResearchHematopoietic stem cellsAcute myeloid leukemiaHuman HSPCsAssociated with poor survivalHematopoietic stem cell stateHuman hematopoietic developmentUmbilical cord bloodAdult bone marrowMature effector cellsLineage-restricted progenitorsBlood diseasesTranscriptional programsCirculating blood cellsCord bloodEngraftment potentialFetal liverEffector cellsHematopoietic stemLymphoid lineagesMyeloid leukemiaHuman hematopoiesisHSPC populationsBone marrowHematopoietic systemPoor survival
2012
A Dual Role of Evi-1 During Developmental Hematopoiesis
Konantz M, Grauer M, Grzywna S, Park I, Daley G, Kanz L, Lengerke C. A Dual Role of Evi-1 During Developmental Hematopoiesis. Blood 2012, 120: 765. DOI: 10.1182/blood.v120.21.765.765.Peer-Reviewed Original ResearchEvi-1Developmental hematopoiesisZebrafish embryosSCL expressionProgenitor cellsHematopoietic cellsPre-mRNA splicingHuman hematopoietic developmentEvi-1 locusMurine hematopoietic cellsHuman iPS cellsPrecise molecular basisSurvival/proliferationEmbryonic myelopoiesisPluripotent stem cellsEvi-1 expressionErythroid progenitor cellsDefinitive hematopoiesisPrimitive erythroid progenitor cellsPrimitive erythropoiesisZebrafish zygotesHSC formationPrimitive hematopoiesisBlood developmentSitu hybridization analysis
2009
Hematopoietic Development from Human Induced Pluripotent Stem Cells
Lengerke C, Grauer M, Niebuhr NI, Riedt T, Kanz L, Park I, Daley GQ. Hematopoietic Development from Human Induced Pluripotent Stem Cells. Annals Of The New York Academy Of Sciences 2009, 1176: 219-227. PMID: 19796250, PMCID: PMC2849804, DOI: 10.1111/j.1749-6632.2009.04606.x.Peer-Reviewed Original ResearchConceptsEmbryonic stem cellsMouse embryonic stem cellsPluripotent stem cellsHematopoietic developmentInduced pluripotent stem cellsHuman induced pluripotent stem cellsHematopoietic stem cellsStem cellsDifferentiated somatic cellsHuman embryonic stem cellsHuman hematopoietic developmentStem cell linesGene expression dataIrradiated adult miceHox genesPluripotent stateBlood lineagesSomatic cellsEctopic expressionCombinatorial overexpressionExpression dataBlood formationIPS cellsColony activityMultilineage reconstitution
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