2025
A social-ecological-technological vulnerability approach for assessing urban hydrological risks
Khromova S, Méndez G, Eckelman M, Herreros-Cantis P, Langemeyer J. A social-ecological-technological vulnerability approach for assessing urban hydrological risks. Ecological Indicators 2025, 173: 113334. PMID: 40255455, PMCID: PMC12006026, DOI: 10.1016/j.ecolind.2025.113334.Peer-Reviewed Original ResearchSocial-ecological-technological systemsExtreme climatic eventsClimatic eventsResilient urban futuresAssess vulnerabilitySewer overflowsRisk indexVulnerability approachClimate changePopulation growthUrban population growthEnvironmental challengesSocially vulnerable communitiesSewer infrastructureFlood eventsSewerUrban geographySocial vulnerabilityVulnerable communitiesUrban futuresVulnerabilityHigh-risk communitiesCommunityMultiple vulnerabilitiesHotspots
2023
The coevolutionary mosaic of bat betacoronavirus emergence risk
Forero-Muñoz N, Muylaert R, Seifert S, Albery G, Becker D, Carlson C, Poisot T. The coevolutionary mosaic of bat betacoronavirus emergence risk. Virus Evolution 2023, 10: vead079. PMID: 38361817, PMCID: PMC10868545, DOI: 10.1093/ve/vead079.Peer-Reviewed Original ResearchSpatially explicit frameworkGeographic mosaic theory of coevolutionHost richnessGeographies of riskExplicit frameworkGeographic mosaic theoryTheory of coevolutionGlobal biogeographySub-Saharan AfricaDisease emergencePathogen evolutionEvolutionary riskSub-SaharanViral emergenceMiddle EastHotspotsSoutheast Asia
2022
Present and future distribution of bat hosts of sarbecoviruses: implications for conservation and public health
Muylaert R, Kingston T, Luo J, Vancine M, Galli N, Carlson C, John R, Rulli M, Hayman D. Present and future distribution of bat hosts of sarbecoviruses: implications for conservation and public health. Proceedings Of The Royal Society B 2022, 289: 20220397. PMID: 35611534, PMCID: PMC9130791, DOI: 10.1098/rspb.2022.0397.Peer-Reviewed Original ResearchConceptsLoss of population connectivityPredictors of species distributionsReservoirs of diverse virusesBiodiversity extinction crisisProject future scenariosModel current distributionHotspots shiftLandscape relationshipsLocal extinctionSpecies distributionHuman encroachmentExtinction crisisSARS-like virusesPopulation connectivityTemperature seasonalityNatural habitatsGlobal changeHost distributionEcological nichesFuture scenariosBat hostsHotspotsDiverse virusesViral spilloverHuman population
2016
Identifying Allosteric Hotspots with Dynamics: Application to Inter- and Intra-species Conservation
Clarke D, Sethi A, Li S, Kumar S, Chang RW, Chen J, Gerstein M. Identifying Allosteric Hotspots with Dynamics: Application to Inter- and Intra-species Conservation. Structure 2016, 24: 826-837. PMID: 27066750, PMCID: PMC4883016, DOI: 10.1016/j.str.2016.03.008.Peer-Reviewed Original ResearchConceptsAllosteric residuesIntra-species conservationEvolutionary time scalesDisease-Associated VariantsProtein conformational changesSelective constraintsAllosteric hotspotsSequencing initiativesOwn proteinsInformation-flow bottlenecksDeep sequencingConformational changesDisease locusBiophysical reasonsResiduesSurface pocketsConservationAllosteryLociSequencingProteinHotspotsPocketPDBVariants
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