2025
Fatigue, physical function, and the context of social vulnerability for older adults with cancer
Jensen-Battaglia M, Delmerico A, Mohamed M, Tylock R, Flannery M, Burnette B, Desai N, Anthony N, Mustian K, Loh K, Mohile S, Seplaki C, Gilmore N. Fatigue, physical function, and the context of social vulnerability for older adults with cancer. Journal Of Geriatric Oncology 2025, 16: 102284. PMID: 40450795, PMCID: PMC12226210, DOI: 10.1016/j.jgo.2025.102284.Peer-Reviewed Original ResearchConceptsSocial determinants of healthPhysical functionOlder adultsShort Physical Performance BatteryEstimate adjusted relative risksCluster randomized clinical trialRelative riskAdvanced cancerCancer-related fatigueDeterminants of healthPhysical Performance BatteryAdjusted relative risksAssociated with increased riskGreater fatigueSocial determinantsPerformance BatteryBaseline fatigueManaging fatigueFollow-up timepointsAssociated with declinesSocial vulnerabilitySocial Vulnerability IndexSPPBPatient-Reported Outcomes Common Terminology Criteria for Adverse EventsCommunity level
2023
Tobacco use and cancer‐related symptom burden: Analysis of the US Population Assessment of Tobacco and Health Study
Price S, Palmer A, Fucito L, Graboyes E, Baker N, Rojewski A, Toll B. Tobacco use and cancer‐related symptom burden: Analysis of the US Population Assessment of Tobacco and Health Study. Cancer 2023, 129: 2385-2394. PMID: 37211959, PMCID: PMC10593116, DOI: 10.1002/cncr.34746.Peer-Reviewed Original ResearchConceptsSymptom burdenCurrent smokingCigarette smokingQuit attemptsTobacco useGreater fatiguePast-year quit attemptsCancer symptom burdenUS Population AssessmentCurrent cigarette smokingGreater symptom burdenTobacco treatment interventionsAdult cancer survivorsQuality of lifeSmoking quit attemptEmotional problemsRace/ethnicityCancer survivorsTobacco cessationHealth StudySmokingTreatment interventionsUS FoodMultivariate analysisSurvivors' interest
2021
Epigenetic age acceleration, fatigue, and inflammation in patients undergoing radiation therapy for head and neck cancer: A longitudinal study
Xiao C, Beitler JJ, Peng G, Levine ME, Conneely KN, Zhao H, Felger JC, Wommack EC, Chico CE, Jeon S, Higgins KA, Shin DM, Saba NF, Burtness BA, Bruner DW, Miller AH. Epigenetic age acceleration, fatigue, and inflammation in patients undergoing radiation therapy for head and neck cancer: A longitudinal study. Cancer 2021, 127: 3361-3371. PMID: 34027995, DOI: 10.1002/cncr.33641.Peer-Reviewed Original ResearchConceptsC-reactive proteinIL-6 levelsEpigenetic age accelerationNeck cancerInterleukin-6Inflammatory markersHigher epigenetic age accelerationLower C-reactive proteinAge accelerationHigher C-reactive proteinMultidimensional Fatigue Inventory-20Poor functional outcomeBlood DNA methylationMonths postradiotherapyAdvanced diseaseConcurrent chemoradiationMost patientsDistant metastasisFunctional outcomeSevere fatigueTreatment completionRadiation therapyPatientsGreater fatigueInflammation
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