2023
Adjuvant chemotherapy does not improve outcome in children with ovarian immature teratoma: A comparative analysis of clinical trial data from the Malignant Germ Cell International Consortium
Vieira A, Puthenpura V, Krailo M, Fallahazad N, Brougham M, Murray M, Frazier A, Lopes L, Pashankar F. Adjuvant chemotherapy does not improve outcome in children with ovarian immature teratoma: A comparative analysis of clinical trial data from the Malignant Germ Cell International Consortium. Pediatric Blood & Cancer 2023, 70: e30426. PMID: 37243320, DOI: 10.1002/pbc.30426.Peer-Reviewed Original ResearchConceptsOvarian immature teratomaOverall survivalImmature teratomaPostoperative chemotherapyBrazilian patientsStage IIAdjuvant chemotherapyUK cohortGrade 1 diseaseGrade 3 patientsReceipt of chemotherapyMainstay of therapyValue of chemotherapyPrimary outcome measureClinical trial dataIT patientsEntire cohortUK patientsRelapse riskBrazilian cohortOutcome measuresPractice variationChemotherapyPatientsStage I
2018
Validation of a new American Association for the Surgery of Trauma (AAST) anatomic severity grading system for acute cholecystitis
Vera K, Pei KY, Schuster KM, Davis KA. Validation of a new American Association for the Surgery of Trauma (AAST) anatomic severity grading system for acute cholecystitis. Journal Of Trauma And Acute Care Surgery 2018, 84: 650-654. PMID: 29271871, DOI: 10.1097/ta.0000000000001762.Peer-Reviewed Original ResearchConceptsLength of stayAcute cholecystitisICU useGrade 2Anatomic gradingAdverse eventsGrade 1Longer LOSAnatomic grading systemGrade 1 diseaseEmergency general surgeryGrade 3 patientsRetrospective cohort studyIncidence of complicationsMajority of patientsTertiary medical centerLow-grade diseaseSurgery of TraumaRisk-adjusted outcomesGood inter-rater reliabilityAAST gradeAmerican AssociationCholecystitis severityCohort studyConsecutive patients
2015
Is adjuvant chemotherapy indicated in ovarian immature teratomas? A combined data analysis from the Malignant Germ Cell Tumor International Collaborative
Pashankar F, Hale JP, Dang H, Krailo M, Brady WE, Rodriguez-Galindo C, Nicholson JC, Murray MJ, Bilmire DF, Stoneham S, Arul GS, Olson TA, Stark D, Shaikh F, Amatruda JF, Covens A, Gershenson DM, Frazier AL. Is adjuvant chemotherapy indicated in ovarian immature teratomas? A combined data analysis from the Malignant Germ Cell Tumor International Collaborative. Cancer 2015, 122: 230-237. PMID: 26485622, PMCID: PMC5134834, DOI: 10.1002/cncr.29732.Peer-Reviewed Original ResearchMeSH KeywordsAdolescentAdultAge FactorsAnalysis of VarianceBiopsy, NeedleChemotherapy, AdjuvantChildCohort StudiesDisease-Free SurvivalFemaleHumansImmunohistochemistryMiddle AgedNeoplasm InvasivenessNeoplasm Recurrence, LocalNeoplasm StagingOvarian NeoplasmsRegistriesRisk AssessmentSurvival AnalysisTeratomaYoung AdultConceptsImmature teratomaAdult clinical trialsGrade 1 diseaseOvarian immature teratomaRole of chemotherapyPostoperative chemotherapyPediatric patientsAdult trialsPediatric trialsPooled analysisClinical trialsStage IAdult womenTrialsChemotherapyCollaborative data setPatientsSurgeryTeratomaDiseaseWomen
2009
Ovarian Preservation and Staging in Reproductive-Age Endometrial Cancer Patients
Richter C, Qian B, Martel M, Yu H, Azodi M, Rutherford T, Schwartz P. Ovarian Preservation and Staging in Reproductive-Age Endometrial Cancer Patients. Obstetrical & Gynecological Survey 2009, 64: 726-727. DOI: 10.1097/01.ogx.0000361368.51892.57.Peer-Reviewed Original ResearchDisease-free survivalLonger disease-free survivalSurgical stagingEndometrial cancerOvarian preservationClinical stagingPremenopausal womenEndometrial carcinomaEarly-stage low-grade endometrial cancerEarly-stage endometrial cancerEarly-stage endometrial carcinomaLow-grade endometrial cancerYoung womenLong-term adverse effectsAggressive surgical stagingGrade 1 diseaseStage endometrial cancerEndometrial cancer patientsStage 1 diseaseTotal abdominal hysterectomyEarly-stage patientsLonger overall survivalLarge university hospitalQuality of lifeParaaortic lymphadenectomyOvarian preservation and staging in reproductive-age endometrial cancer patients
Richter CE, Qian B, Martel M, Yu H, Azodi M, Rutherford TJ, Schwartz PE. Ovarian preservation and staging in reproductive-age endometrial cancer patients. Gynecologic Oncology 2009, 114: 99-104. PMID: 19410280, DOI: 10.1016/j.ygyno.2009.03.032.Peer-Reviewed Original ResearchConceptsDisease-free survivalLonger disease-free survivalYale-New Haven HospitalEndometrial cancer patientsOvarian preservationSurgical stagingOverall survivalEndometrial cancerCancer patientsEarly-stage low-grade endometrial cancerStage IYoung endometrial cancer patientsBetter disease-free survivalLow-grade endometrial cancerGrade 1 diseaseRetrospective chart reviewLonger overall survivalChart reviewYounger patientsClinical stagingSurgical treatmentEndometrial carcinomaGynecologic pathologistsRisk factorsAge 45
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