2024
Clinical Implications of C2 Lesion in IgA Nephropathy: A Cohort Study
Wang Z, Zhou X, Shi S, Liu L, Lv J, Zhang H. Clinical Implications of C2 Lesion in IgA Nephropathy: A Cohort Study. American Journal Of Nephrology 2024, 55: 529-538. PMID: 39074466, DOI: 10.1159/000540268.Peer-Reviewed Original ResearchConceptsEnd-stage kidney diseaseC2 lesionsCohort studyCox regressionMonths prior to biopsyPeking University First HospitalProportion of crescentsMultivariate Cox regressionProspective cohort studyEffective treatment strategiesKidney prognosisImmunosuppressive treatmentRenal prognosisT2 lesionsMean proteinuriaCombined steroidCrescentic lesionsOxford classificationGlomerular crescentsClinical prognosisUnivariate analysisPathological findingsClinical significanceIgA nephropathyKidney function
2019
Tubulointerstitial Infiltration of M2 Macrophages in Henoch‐Schönlein Purpura Nephritis Indicates the Presence of Glomerular Crescents and Bad Clinical Parameters
Kim J, Choi S, Lee K, Jeong H, Shin J, Lim B. Tubulointerstitial Infiltration of M2 Macrophages in Henoch‐Schönlein Purpura Nephritis Indicates the Presence of Glomerular Crescents and Bad Clinical Parameters. BioMed Research International 2019, 2019: 8579619. PMID: 30800680, PMCID: PMC6360621, DOI: 10.1155/2019/8579619.Peer-Reviewed Original ResearchConceptsClass III-IVChronic renal failureAssociated with chronic renal failureHenoch-Schonlein purpuraIII-IVISKDC classificationClinical parametersGlomerular crescentsInternational Study of Kidney DiseaseM2 macrophagesPresence of glomerular crescentsPresence of chronic renal failureAssociated with disease progressionInfiltration of M2 macrophagesInfiltration of M1Subtypes of macrophagesStudy of Kidney DiseaseTubulointerstitial infiltrationRenal involvementSystemic vasculitisISKDCRenal failureHistological featuresSevere manifestationsBorderline significance
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