2018
Establishment of a continuous in vitro culture of Babesia duncani in human erythrocytes reveals unusually high tolerance to recommended therapies
Abraham A, Brasov I, Thekkiniath J, Kilian N, Lawres L, Gao R, DeBus K, He L, Yu X, Zhu G, Graham MM, Liu X, Molestina R, Ben Mamoun C. Establishment of a continuous in vitro culture of Babesia duncani in human erythrocytes reveals unusually high tolerance to recommended therapies. Journal Of Biological Chemistry 2018, 293: 19974-19981. PMID: 30463941, PMCID: PMC6311517, DOI: 10.1074/jbc.ac118.005771.Peer-Reviewed Original ResearchConceptsHuman babesiosisBetter therapeutic strategiesHigher parasite burdenTick-borne diseaseFulminant infectionRed blood cellsTherapeutic strategiesHuman erythrocytesParasite burdenClinical casesSevere pathologyHuman red blood cellsNew disease modelsBlood cellsDisease modelsInfectionDiseaseBabesiosisDeathRelevant model systemParasitesApicomplexan parasitesDaughter parasitesErythrocytesFurther research
2012
Comment on “Epidermal Growth Factor Receptor Is Essential for Toll-Like Receptor 3 Signaling”
Burtness B, Marur S, Bauman JE, Golemis EA, Mehra R, Cohen SJ. Comment on “Epidermal Growth Factor Receptor Is Essential for Toll-Like Receptor 3 Signaling”. Science Signaling 2012, 5: lc5. PMID: 23233526, DOI: 10.1126/scisignal.2003734.Peer-Reviewed Original ResearchConceptsEpidermal growth factor receptorGrowth factor receptorToll-like receptor 3Functional innate immune responseFactor receptorInnate immune responseFulminant infectionCombination therapyImmune responseTumor growthReceptor 3Mammalian targetCancer therapeuticsReceptorsMTORPatientsBody of literatureTherapyTumorsInfection
2006
Fatal Factitious Cushing’s Syndrome and Invasive Aspergillosis: Case Report and Review of Literature
Kansagara DL, Tetrault J, Hamill C, Moore C, Olson B. Fatal Factitious Cushing’s Syndrome and Invasive Aspergillosis: Case Report and Review of Literature. Endocrine Practice 2006, 12: 651-655. PMID: 17229661, DOI: 10.4158/ep.12.6.651.Peer-Reviewed Case Reports and Technical NotesConceptsFactitious Cushing's syndromeCushing's syndromeInvasive aspergillosisDiffuse pulmonary infiltratesUntreated Cushing's syndromeFatal septic shockInvasive pulmonary aspergillosisMechanism of immunosuppressionInvasive fungal infectionsHealth care providersReview of literaturePulmonary infiltratesFulminant infectionSeptic shockImmunologic aspectsPulmonary aspergillosisClinical findingsCase reportFatal conditionDifficult diagnosisAdrenal cortexTreatment considerationsFactitious illnessPatient's homeSyndrome
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