2024
Transcriptional Profiling Underscores the Role of Preprocurement Allograft Metabolism and Innate Immune Status on Outcomes in Human Liver Transplantation
Kim J, Zimmermann M, Mathison A, Lomberk G, Urrutia R, Hong J. Transcriptional Profiling Underscores the Role of Preprocurement Allograft Metabolism and Innate Immune Status on Outcomes in Human Liver Transplantation. Annals Of Surgery Open 2024, 5: e444-e444. PMID: 38911661, PMCID: PMC11191965, DOI: 10.1097/as9.0000000000000444.Peer-Reviewed Original ResearchOrthotopic liver transplantationIschemia-reperfusion injuryCold ischemiaLiver transplantationPrimary orthotopic liver transplantationGraft ischemia-reperfusion injuryClinical orthotopic liver transplantationEffects of ischemia-reperfusion injuryLiver graft ischemia-reperfusion injuryHuman orthotopic liver transplantationTherapeutic targetLiver allograft biopsiesHuman liver transplantationInflammatory response genesIAF groupAllograft injuryDecreased metabolic activityAllograft dysfunctionAllograft functionAllograft biopsiesGene expressionSurrogate markerFatty acid-metabolizing activitiesMetabolic activityHistological evaluation
2023
Allograft tissue under the microscope: only the beginning
Virmani S, Rao A, Menon M. Allograft tissue under the microscope: only the beginning. Current Opinion In Organ Transplantation 2023, 28: 126-132. PMID: 36787238, PMCID: PMC10214011, DOI: 10.1097/mot.0000000000001052.Peer-Reviewed Original ResearchConceptsAllograft tissueArtificial intelligenceBanff schemaMachine learningDigital pathologyKidney allograft biopsiesApplication of AINovel molecular diagnosticsAllograft healthAllograft histologyAllograft biopsiesPathologic diagnosisImmunological activationTissue injuryHistopathological analysisClinical careTissue pathologyML algorithmsClinical useOrdinal outputsNovel modalityVivo microscopyPathologyBiopsyTissue
2010
ADVERSE IMPACT OF MILD HYPERTENSION POST TRANSPLANT ON 1 YEAR CHRONIC INTERSTIAL FIBROSIS AND TUBULAR ATROPY SCORES IN KIDNEY ALLOGRAFT BIOPSY AMONG A COHORT ON RAPID STEROID WITHDRAWL PROTOCOL.
Chakkera H, Devarapalli Y, Mulligan D, Mazur M, Hamawi K, Reddy K, Moss A, Mekeel K, Heilman R. ADVERSE IMPACT OF MILD HYPERTENSION POST TRANSPLANT ON 1 YEAR CHRONIC INTERSTIAL FIBROSIS AND TUBULAR ATROPY SCORES IN KIDNEY ALLOGRAFT BIOPSY AMONG A COHORT ON RAPID STEROID WITHDRAWL PROTOCOL. Transplantation 2010, 90: 387. DOI: 10.1097/00007890-201007272-00715.Peer-Reviewed Original Research
1992
Expression of vascular cell adhesion molecule-1 in human renal allografts.
Briscoe DM, Pober JS, Harmon WE, Cotran RS. Expression of vascular cell adhesion molecule-1 in human renal allografts. Journal Of The American Society Of Nephrology 1992, 3: 1180-5. PMID: 1282831, DOI: 10.1681/asn.v351180.Peer-Reviewed Original ResearchMeSH KeywordsAcute DiseaseAntigens, CDAntigens, Differentiation, MyelomonocyticCD3 ComplexCell Adhesion MoleculesEndothelium, VascularE-SelectinGraft RejectionHumansIntercellular Adhesion Molecule-1Kidney TransplantationKidney Tubular Necrosis, AcuteKidney TubulesMacrophagesMonocytesPostoperative ComplicationsT-Lymphocyte SubsetsTransplantation, HomologousVascular Cell Adhesion Molecule-1ConceptsVascular cell adhesion molecule-1Cell adhesion molecule-1VCAM-1 expressionAdhesion molecule-1Renal allograftsNormal biopsiesMolecule-1Human renal allograft biopsiesMonocyte/macrophage infiltrateEndothelial VCAM-1 expressionAcute tubular necrosisRenal allograft biopsiesT-cell infiltratesT cell infiltrationHuman renal allograftsEndothelial VCAM-1Normal kidney specimensArea of infiltratesMean scoreVascular endothelial cellsAcute rejectionAllograft biopsiesTubular necrosisCell infiltrateClinicopathologic diagnosis
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