Transcriptional Profiling Underscores the Role of Preprocurement Allograft Metabolism and Innate Immune Status on Outcomes in Human Liver Transplantation
Kim J, Zimmermann M, Mathison A, Lomberk G, Urrutia R, Hong J. Transcriptional Profiling Underscores the Role of Preprocurement Allograft Metabolism and Innate Immune Status on Outcomes in Human Liver Transplantation. Annals Of Surgery Open 2024, 5: e444-e444. PMID: 38911661, PMCID: PMC11191965, DOI: 10.1097/as9.0000000000000444.Peer-Reviewed Original ResearchOrthotopic liver transplantationIschemia-reperfusion injuryCold ischemiaLiver transplantationPrimary orthotopic liver transplantationGraft ischemia-reperfusion injuryClinical orthotopic liver transplantationEffects of ischemia-reperfusion injuryLiver graft ischemia-reperfusion injuryHuman orthotopic liver transplantationTherapeutic targetLiver allograft biopsiesHuman liver transplantationInflammatory response genesIAF groupAllograft injuryDecreased metabolic activityAllograft dysfunctionAllograft functionAllograft biopsiesGene expressionSurrogate markerFatty acid-metabolizing activitiesMetabolic activityHistological evaluation
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