2025
Rotational Power: A New Accelerometer-Derived Metric to Assess Functional Impairment in Multiple Sclerosis
Mascia G, Meyer B, Cherian J, Kairamkonda D, Fanning J, Rice P, Sosnoff J, Solomon A, McGinnis E, McGinnis R. Rotational Power: A New Accelerometer-Derived Metric to Assess Functional Impairment in Multiple Sclerosis. IEEE Transactions On Neural Systems And Rehabilitation Engineering 2025, 33: 3096-3104. PMID: 40742863, PMCID: PMC12406280, DOI: 10.1109/tnsre.2025.3594540.Peer-Reviewed Original ResearchConceptsSit-to-standStand-to-sitAcute fatigueActivities Specific Balance Confidence ScaleModified Fatigue Impact ScaleBalance Confidence ScaleChair stand testPeak mechanical powerFree-Living SettingsFatigue Impact ScaleRotational powerMotion capture systemMuscular strengthMultiple sclerosisConfidence ScaleImpact ScaleImpaired mobilityLower limbsFunctional performanceMechanical powerFunctional assessmentClinical measuresSignificant associationFunctional impairmentBody-mass
2009
Fatigue in multiple sclerosis is associated with the disruption of frontal and parietal pathways
Sepulcre J, Masdeu J, Goñi J, Arrondo G, Vélez de Mendizábal N, Bejarano B, Villoslada P. Fatigue in multiple sclerosis is associated with the disruption of frontal and parietal pathways. Multiple Sclerosis Journal 2009, 15: 337-344. PMID: 18987107, DOI: 10.1177/1352458508098373.Peer-Reviewed Original ResearchConceptsMultiple sclerosisGray matter atrophyWhite matter lesion locationFatigue scoresLocation of white matter lesionsModified Fatigue Impact ScaleWhite matter lesionsMagnetic resonance imagingVoxel-based morphometry methodFatigue Impact ScaleAtrophy degreeWhite matter regionsMS-related fatigueBilateral middle frontal gyriSymptoms of fatigueLeft superior frontal gyrusLesion loadCognitive/attentional processesPatients' qualityLesion locationResonance imagingSuperior frontal gyrusImpact ScaleLesionsMiddle frontal gyri
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