2024
Dietary intake of plant- and animal-derived protein and incident cardiovascular diseases: the pan-European EPIC-CVD case–cohort study
Zheng J, Steur M, Imamura F, Freisling H, Johnson L, van der Schouw Y, Tong T, Weiderpass E, Bajracharya R, Crous-Bou M, Dahm C, Heath A, Ibsen D, Jannasch F, Katzke V, Masala G, Moreno-Iribas C, Sacerdote C, Schulze M, Sieri S, Wareham N, Danesh J, Butterworth A, Forouhi N. Dietary intake of plant- and animal-derived protein and incident cardiovascular diseases: the pan-European EPIC-CVD case–cohort study. American Journal Of Clinical Nutrition 2024, 119: 1164-1174. PMID: 38479550, PMCID: PMC11130694, DOI: 10.1016/j.ajcnut.2024.03.006.Peer-Reviewed Original ResearchConceptsIschemic heart diseaseDietary protein intakeProtein intakeCase-cohort studyCardiovascular diseaseIncident cardiovascular diseaseFatal strokeAssociated with lower incidenceIncidence of fatal strokeRisk of cardiovascular diseaseEuropean Prospective InvestigationPrentice-weighted Cox regressionAssociated with incident cardiovascular diseaseOverall CVDIncident CVD casesIntake of plantMacronutrient intakeStroke incidenceProtein consumptionSubcohort membersIsocaloric substitutionDietary patternsDietary intakeNever smokersProspective Investigation
2023
Targeted drug delivery to the brain endothelium dominates over passive delivery via vascular leak in experimental intracerebral hemorrhage
Reyes-Esteves S, Nong J, Glassman P, Omo-Lamai S, Ohashi S, Myerson J, Zamora M, Ma X, Kasner S, Sansing L, Muzykantov V, Marcos-Contreras O, Brenner J. Targeted drug delivery to the brain endothelium dominates over passive delivery via vascular leak in experimental intracerebral hemorrhage. Journal Of Controlled Release 2023, 356: 185-195. PMID: 36868517, PMCID: PMC10519578, DOI: 10.1016/j.jconrel.2023.02.037.Peer-Reviewed Original ResearchConceptsIntracerebral hemorrhageVascular leakBrain accumulationEarly time pointsBrain endotheliumClinical ICHTime pointsExperimental intracerebral hemorrhageSpecific drug therapyBlood-brain barrierFatal strokeICH inductionIntrastriatal injectionICH onsetDrug therapyHematoma expansionImmune attackBrain deliveryCommon causeVascular endotheliumBlood leakDrug accumulationIntravenous deliveryBrain regionsHemorrhage
2017
Incidental Thrombus in Transit Causing Embolic Stroke
Malm B, Hermany P, Morrison A. Incidental Thrombus in Transit Causing Embolic Stroke. Case Reports In Medicine 2017, 2017: 3161972. PMID: 28713430, PMCID: PMC5496107, DOI: 10.1155/2017/3161972.Peer-Reviewed Case Reports and Technical Notes
2015
A rare case of fatal stroke after ethylene glycol toxicity
Garg D, Lim T, Irani M. A rare case of fatal stroke after ethylene glycol toxicity. BMJ Case Reports 2015, 2015: bcr2014208855. PMID: 25809433, PMCID: PMC4386312, DOI: 10.1136/bcr-2014-208855.Peer-Reviewed Original ResearchConceptsEthylene glycol toxicityGlycol toxicityAcute left-sided weaknessFurther blood testsLeft-sided weaknessSerum osmolal gapNeurological improvementFatal strokeAcute infarctionGeneralised oedemaBlood testsEmergency departmentOsmolal gapAnion gapBrain MRIRare casePatientsVisual fieldAcetone odorMOsm/StrokeToxicityTimely fashionDaysFomepizole
2001
A Clinical Trial of Estrogen-Replacement Therapy after Ischemic Stroke
Viscoli C, Brass L, Kernan W, Sarrel P, Suissa S, Horwitz R. A Clinical Trial of Estrogen-Replacement Therapy after Ischemic Stroke. New England Journal Of Medicine 2001, 345: 1243-1249. PMID: 11680444, DOI: 10.1056/nejmoa010534.Peer-Reviewed Original ResearchConceptsEstrogen replacement therapyEstrogen therapyNonfatal strokePostmenopausal womenIschemic strokeCerebrovascular diseasePlacebo-controlled trialTransient ischemic attackOccurrence of strokeRisk of deathIschemic attackFatal strokeMean followPlacebo groupSecondary preventionEstradiol groupFunctional deficitsClinical trialsObservational studyHigh riskWoman's riskTherapyStrokeWomenDeath
1998
Usefulness of Transesophageal Echocardiography in Predicting Mortality and Morbidity in Stroke Patients Without Clinically Known Cardiac Sources of Embolus 11The views expressed in this article are those of the authors and do not reflect the official policy of the United States Navy, Department of Defense, or the United States Government.
O’Brien P, Thiemann D, McNamara R, Roberts J, Raska K, Oppenheimer S, Lima J. Usefulness of Transesophageal Echocardiography in Predicting Mortality and Morbidity in Stroke Patients Without Clinically Known Cardiac Sources of Embolus 11The views expressed in this article are those of the authors and do not reflect the official policy of the United States Navy, Department of Defense, or the United States Government. The American Journal Of Cardiology 1998, 81: 1144-1151. PMID: 9605057, DOI: 10.1016/s0002-9149(98)00132-5.Peer-Reviewed Original ResearchConceptsSpontaneous echo contrastRecurrent strokeTransesophageal echocardiographyMyocardial infarctionEcho contrastAtrial spontaneous echo contrastMitral valve strandsNonfatal myocardial infarctionTransient ischemic attackIschemic stroke patientsMitral annular calcificationMitral valve thickeningRecent myocardial infarctionAtrial septal defectMultiplane transesophageal echocardiographyAscending aorticCardiovascular survivalHeart thrombusIschemic attackPeripheral embolismAortic atherosclerosisCardiac causesFatal strokeVascular causesAnnular calcification
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