2025
EP6.49 Sexual Function May Improve After Hip Arthroscopy: A Systematic Review
Lee M, MacLeod J, Sharda M, Mohiuddin A, Girardi K, Jonnalagadda A, Darby F, Park N, Mahatme R, Fong S, Moran J, Jimenez A. EP6.49 Sexual Function May Improve After Hip Arthroscopy: A Systematic Review. Journal Of Hip Preservation Surgery 2025, 12: i105-i105. PMCID: PMC11954038, DOI: 10.1093/jhps/hnaf011.338.Peer-Reviewed Original ResearchCochrane Controlled Register of TrialsPatient-reported outcomesHip arthroscopyFemoroacetabular impingementSystematic reviewInternational Hip Outcome Tool-12Sexual activitySexual functionNerve-related complicationsErectile Function scoreSexual activity questionAssociated with painFemoroacetabular impingement patientsCochrane Controlled RegisterPreferred Reporting ItemsPostoperative patients' scoresRegister of TrialsImpact quality of lifeOutcomes of sexual functionResume sexual activityQuality of lifePostoperative PROsMedian timeOriginal research articlesSexual Functioning ScaleRates of Return to Sexual Activity Are High In Patients Undergoing Hip Arthroscopy And Occurs Within Six Weeks Postoperatively In Most Patients: A Systematic Review
Lee M, Sharda M, Mohiuddin A, Girardi K, Jonnalagadda A, Darby F, Park N, Mahatme R, Gillinov S, Surucu S, Moran J, Jimenez A. Rates of Return to Sexual Activity Are High In Patients Undergoing Hip Arthroscopy And Occurs Within Six Weeks Postoperatively In Most Patients: A Systematic Review. Arthroscopy The Journal Of Arthroscopic And Related Surgery 2025 PMID: 39826664, DOI: 10.1016/j.arthro.2025.01.007.Peer-Reviewed Original Research In PressCochrane Controlled Register of TrialsPatient-reported outcomesHip arthroscopySexual functionSystematic reviewFemale Sexual Function ScaleInternational Hip Outcome Tool-12Sexual activityPostoperative sexual functionNerve-related complicationsErectile Function scoreSexual activity questionFollow-up periodAssociated with higher ratesMedian patient scoreResumption of sexual activityCochrane Controlled RegisterReturn to sexual activityPreferred Reporting ItemsRegister of TrialsOutcomes of sexual functionResume sexual activityIIEF-5Postoperative PROsSignificant improvement
2019
Nerve Growth Factor Improves the Outcome of Type 2 Diabetes—Induced Hypotestosteronemia and Erectile Dysfunction
Wu Y, Yang C, Meng F, Que F, Xiao W, Rao H, Wan Y, Taylor HS, Lu L. Nerve Growth Factor Improves the Outcome of Type 2 Diabetes—Induced Hypotestosteronemia and Erectile Dysfunction. Reproductive Sciences 2019, 26: 386-393. PMID: 29724155, DOI: 10.1177/1933719118773421.Peer-Reviewed Original ResearchConceptsNerve growth factorErectile dysfunctionTotal testosteroneFree testosteroneDiabetes-induced erectile dysfunctionNGF treatmentGrowth factorHyperglycemia-induced downregulationErectile Function scoreIIEF-5 scoreSerum total testosteroneType 2 diabetesMouse Leydig cellsSteroidogenic acute regulatory proteinDiabetic malesSensorimotor polyneuropathySerum testosteroneFunction scoresAcute regulatory proteinInternational IndexClinical studiesED outcomesCytochrome P450 11A1Testosterone biosynthesisLeydig cells
2006
Single-Blind, Multicenter, Placebo Controlled, Parallel Study to Assess the Safety and Efficacy of Intralesional Interferon α-2b for Minimally Invasive Treatment for Peyronie’s Disease
Hellstrom WJ, Kendirci M, Matern R, Cockerham Y, Myers L, Sikka SC, Venable D, Honig S, McCullough A, Hakim LS, Nehra A, Templeton LE, Pryor JL. Single-Blind, Multicenter, Placebo Controlled, Parallel Study to Assess the Safety and Efficacy of Intralesional Interferon α-2b for Minimally Invasive Treatment for Peyronie’s Disease. Journal Of Urology 2006, 176: 394-398. PMID: 16753449, DOI: 10.1016/s0022-5347(06)00517-9.Peer-Reviewed Original ResearchConceptsIntralesional interferon alpha-2bAlpha-2bInterferon alpha-2bPeyronie's diseasePenile curvatureInterferon alpha-2b therapyPlaque sizeAlpha-2b therapyIntralesional interferon αMean International IndexErectile Function scoreFlu-like symptomsBlood flow improvementParallel studyPenile painPlacebo-ControlledPain resolutionConsecutive patientsErectile functionFunction scoresMean ageControl armInternational IndexInvasive treatmentStudy completion
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