Drebrin Regulates Collateral Axon Branching in Cortical Layer II/III Somatosensory Neurons
Dorskind J, Sudarsanam S, Hand R, Ziak J, Amoah-Dankwah M, Guzman-Clavel L, Soto-Vargas J, Kolodkin A. Drebrin Regulates Collateral Axon Branching in Cortical Layer II/III Somatosensory Neurons. Journal Of Neuroscience 2023, 43: 7745-7765. PMID: 37798130, PMCID: PMC10648559, DOI: 10.1523/jneurosci.0553-23.2023.Peer-Reviewed Original ResearchConceptsLoss-of-functionCollateral axonal branchingMolecular mechanismsF-actin bundlesStructure-function analysisCircuit formationAxon collateral branchesCortical circuit formationAxonal branchesPyramidal excitatory neuronsLoss-of-function experimentsFemale mouse modelProtein domainsF-actinCortical neuronal morphologyLaminar-specific mannerBranch initiationGene expressionSynaptic partnersSingle-cell labelingAxonal protrusionsDrebrinExcitatory neuronsSomatosensory neuronsDBN1
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