2020
PIWI–piRNA pathway-mediated transposable element repression in Hydra somatic stem cells
Teefy BB, Siebert S, Cazet JF, Lin H, Juliano CE. PIWI–piRNA pathway-mediated transposable element repression in Hydra somatic stem cells. RNA 2020, 26: 550-563. PMID: 32075940, PMCID: PMC7161359, DOI: 10.1261/rna.072835.119.Peer-Reviewed Original ResearchConceptsPIWI-piRNA pathwayTE expressionSomatic stem cellsTransposable elementsTE transcriptsStem cellsFreshwater cnidarianSmall RNA pathwaysTransposable element repressionSomatic cell lineagesGermline of animalsInterstitial stem cellsStem cell populationInterstitial lineageSomatic piRNAsDegradome sequencingEpithelial cellsAncestral functionRNA pathwaysGermline piRNAsPIWI proteinsTE repressionGermline competenceSequence signaturesRNA immunoprecipitation
2016
Genome-Wide Analysis of Polyadenylation Events in Schmidtea mediterranea
Lakshmanan V, Bansal D, Kulkarni J, Poduval D, Krishna S, Sasidharan V, Anand P, Seshasayee A, Palakodeti D. Genome-Wide Analysis of Polyadenylation Events in Schmidtea mediterranea. G3: Genes, Genomes, Genetics 2016, 6: 3035-3048. PMID: 27489207, PMCID: PMC5068929, DOI: 10.1534/g3.116.031120.Peer-Reviewed Original ResearchMeSH Keywords3' Untranslated RegionsAnimalsComputational BiologyGenome, HelminthGenome-Wide Association StudyHigh-Throughput Nucleotide SequencingMicroRNAsMolecular Sequence AnnotationPlatyhelminthsPoly APolyadenylationReproducibility of ResultsRNA InterferenceRNA Processing, Post-TranscriptionalRNA, MessengerConceptsSchmidtea mediterraneaAdvent of next-generation sequencing technologiesNext-generation sequencing technologiesGene expressionTissue-specific expression patternsMiRNA mediated gene regulationGenome-wide scaleGenome-wide analysisPoly(A) sitePosttranscriptional gene expressionRegulate posttranscriptional gene expressionGene annotationInternal exonsPolyadenylated transcriptsTranscript isoformsPolyadenylation eventsDegradome sequencingProtein domainsSequencing technologiesPre-mRNAGene regulationCoding sequenceIdeal model systemStem cell functionFreshwater planarians
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