2024
Kidney Transplant Outcomes From Deceased Donors Who Received Dialysis
Wen Y, Mansour S, Srialluri N, Hu D, Philbrook H, Hall I, Doshi M, Mohan S, Reese P, Parikh C. Kidney Transplant Outcomes From Deceased Donors Who Received Dialysis. JAMA 2024, 332: 215-225. PMID: 38780515, PMCID: PMC11117155, DOI: 10.1001/jama.2024.8469.Peer-Reviewed Original ResearchDeath-censored graft failureKidney transplant recipientsGraft failureDeceased kidney donorsKidney transplantationTransplant recipientsGraft functionDeceased donorsFollow-upHigher risk of delayed graft functionIncidence of delayed graft functionOutcomes of transplant recipientsRisk of delayed graft functionMedian Follow-UpKidney donorsDelayed graft functionUS organ procurement organizationsKidney transplant outcomesRetrospective cohort studyRecipients of kidneysKidney donation
2017
Performance of Serum Creatinine and Kidney Injury Biomarkers for Diagnosing Histologic Acute Tubular Injury
Moledina DG, Hall IE, Thiessen-Philbrook H, Reese PP, Weng FL, Schröppel B, Doshi MD, Wilson FP, Coca SG, Parikh CR. Performance of Serum Creatinine and Kidney Injury Biomarkers for Diagnosing Histologic Acute Tubular Injury. American Journal Of Kidney Diseases 2017, 70: 807-816. PMID: 28844586, PMCID: PMC5701867, DOI: 10.1053/j.ajkd.2017.06.031.Peer-Reviewed Original ResearchMeSH KeywordsAcute Kidney InjuryAdultArea Under CurveBiomarkersCohort StudiesCreatinineCross-Sectional StudiesFatty Acid-Binding ProteinsFemaleHepatitis A Virus Cellular Receptor 1HumansInterleukin-18Kidney TransplantationKidney TubulesLipocalin-2MaleMiddle AgedProspective StudiesROC CurveSeverity of Illness IndexTissue DonorsConceptsSevere acute tubular injuryAcute kidney injuryAcute tubular injuryTubular injurySCr concentrationNGAL concentrationsUrinary biomarkersDeceased donorsOrgan procurementMulticenter prospective cohortUrinary L-FABPUrinary NGAL concentrationsDeceased kidney donorsKidney injury biomarkersSerum creatinine concentrationPoor diagnostic performanceAKI casesAKI causesDonor hospitalizationKidney injuryProspective cohortSerum creatinineInjury biomarkersKidney biopsyIL-18Associations Between Deceased-Donor Urine MCP-1 and Kidney Transplant Outcomes
Mansour SG, Puthumana J, Reese PP, Hall IE, Doshi MD, Weng FL, Schröppel B, Thiessen-Philbrook H, Bimali M, Parikh CR. Associations Between Deceased-Donor Urine MCP-1 and Kidney Transplant Outcomes. Kidney International Reports 2017, 2: 749-758. PMID: 28730184, PMCID: PMC5512592, DOI: 10.1016/j.ekir.2017.03.007.Peer-Reviewed Original ResearchDelayed graft functionAcute kidney injuryMonocyte chemoattractant protein-1MCP-1 concentrationsUMCP-1Graft failureDonor Acute Kidney InjuryRecipient delayed graft functionUrine MCP-1Deceased kidney donorsKidney transplant outcomesChemoattractant protein-1Organ procurement organizationsMinimal clinical utilityAllograft functionAllograft outcomesGraft functionKidney injuryTransplant outcomesKidney procurementStudy cohortKidney donorsIndependent associationMacrophage recruitmentClinical utility
2016
YKL-40 Associates with Renal Recovery in Deceased Donor Kidney Transplantation
Puthumana J, Hall IE, Reese PP, Schröppel B, Weng FL, Thiessen-Philbrook H, Doshi MD, Rao V, Lee CG, Elias JA, Cantley LG, Parikh CR. YKL-40 Associates with Renal Recovery in Deceased Donor Kidney Transplantation. Journal Of The American Society Of Nephrology 2016, 28: 661-670. PMID: 27451287, PMCID: PMC5280016, DOI: 10.1681/asn.2016010091.Peer-Reviewed Original ResearchConceptsYKL-40 concentrationsDonor kidneysYKL-40Renal recoveryDeceased donor kidney transplantationRisk of DGFAcute tubular necrosisDeceased kidney donorsDonor kidney transplantationProspective cohort studyPoor transplant outcomesDeceased donor kidneysOrgan procurement organizationsDonor biomarkersGraft functionKidney transplantationCohort studyGraft failureTransplant outcomesTubular injuryTubular necrosisRecipient outcomesKidney donorsProcurement biopsiesPrognostic biomarker
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