2025
Prevention and treatment of noise-induced hearing loss and cochlear synapse degeneration by potassium channel blockers in vivo
Zhao H, Liu L, Lu X, Quinonez A, Roberts R, Zhai T, Liang C. Prevention and treatment of noise-induced hearing loss and cochlear synapse degeneration by potassium channel blockers in vivo. Hearing Research 2025, 464: 109319. PMID: 40450915, DOI: 10.1016/j.heares.2025.109319.Peer-Reviewed Original ResearchNoise-induced hearing lossDistortion product otoacoustic emissionsAuditory brainstem responseNoise exposureHearing lossAcoustic startle responseTreatment of noise-induced hearing lossHidden hearing lossSystemic administrationInduce hearing lossGAL-021Active cochlear mechanicsChannel blockersOtoacoustic emissionsBrainstem responseHearing disordersAmeliorating noise-induced hearing lossCochlear mechanicsPost-exposure administrationSynapse degenerationInner hair cellsBK channelsAdministration timeIntraperitoneal injectionPharmacological treatment
2015
Pannexin 1 deficiency can induce hearing loss
Zhao H, Zhu Y, Liang C, Chen J. Pannexin 1 deficiency can induce hearing loss. Biochemical And Biophysical Research Communications 2015, 463: 143-147. PMID: 26002464, PMCID: PMC4464954, DOI: 10.1016/j.bbrc.2015.05.049.Peer-Reviewed Original ResearchConceptsDistortion product otoacoustic emissionsHearing lossAuditory brainstem response recordingsProgressive hearing lossProduct otoacoustic emissionsHigh incidenceCell degenerationOtoacoustic emissionsGap junction proteinAcoustic stimulationCell apoptotic pathwaysHair cellsResponse recordingsGene mutationsJunction proteinsExtensive expressionCochleaActive cochlear mechanicsGap junctionsApoptotic pathwayDeficiencyHearingCritical roleCochlear mechanics
1997
Cochlear Mechanics and Biophysics
Ruggero M, Santos‐Sacchi J. Cochlear Mechanics and Biophysics. 1997, 1357-1369. DOI: 10.1002/9780470172537.ch108.Peer-Reviewed Original ResearchCochlear mechanicsCochlea
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