The predictive value of SS-16 in clinically diagnosed Parkinson’s disease patients: comparison with 99mTc-TRODAT-1 SPECT scans
Kang W, Dong F, Li D, Quinn T, Chen S, Liu J. The predictive value of SS-16 in clinically diagnosed Parkinson’s disease patients: comparison with 99mTc-TRODAT-1 SPECT scans. Translational Neurodegeneration 2016, 5: 15. PMID: 27547386, PMCID: PMC4992567, DOI: 10.1186/s40035-016-0062-4.Peer-Reviewed Original ResearchSS-16Positive predictive valueDAT-SPECTPD patientsNegative predictive valueDAT-SPECT scansEarly stage PD patientsNigrostriatal dopaminergic functionNon-parkinsonian syndromesPredictive valueParkinson's diseaseDopaminergic functionOlfactory assessmentBackgroundDopamine transporterOlfactory functionParkinson's disease patientsDiagnosis of PDChinese PD patientsSPECT scansMethodsFifty-twoDiagnostic performanceDiagnostic accuracyPatientsGold standardDisease patientsEffect of a Leucine-rich Repeat Kinase 2 Variant on Motor and Non-motor Symptoms in Chinese Parkinson’s Disease Patients
Sun Q, Wang T, Jiang T, Huang P, Li D, Wang Y, Xiao Q, Liu J, Chen S. Effect of a Leucine-rich Repeat Kinase 2 Variant on Motor and Non-motor Symptoms in Chinese Parkinson’s Disease Patients. Aging And Disease 2016, 7: 230-236. PMID: 27330837, PMCID: PMC4898919, DOI: 10.14336/ad.2015.1026.Peer-Reviewed Original ResearchVariant carriersREM sleep behavior disorderG2385R variantLevodopa equivalent doseREM sleep behavior disorder symptomsLeucine-rich repeat kinase 2PIGD phenotypeChinese Parkinson's disease patientsPostural instabilityGait difficultyPD patientsAssociated with motor fluctuationsMotor fluctuationsNon-motor symptomsLRRK2 variantsRisk factorsChinese populationAsian populationsIdiopathic PDNon-carriersSleep behavior disorderChinese PD patientsLeucine-rich repeat kinase 2 geneParkinson's diseasePIGD
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