2022
Oxygen Supplementation and Hyperoxia in Critically Ill Cardiac Patients From Pathophysiology to Clinical Practice
Thomas A, van Diepen S, Beekman R, Sinha SS, Brusca SB, Alviar CL, Jentzer J, Bohula EA, Katz JN, Shahu A, Barnett C, Morrow DA, Gilmore EJ, Solomon MA, Miller PE. Oxygen Supplementation and Hyperoxia in Critically Ill Cardiac Patients From Pathophysiology to Clinical Practice. JACC Advances 2022, 1: 100065. PMID: 36238193, PMCID: PMC9555075, DOI: 10.1016/j.jacadv.2022.100065.Peer-Reviewed Reviews, Practice Guidelines, Standards, and Consensus StatementsOxygen supplementationIntensive care unit cliniciansHarmful hemodynamic effectsAdverse clinical outcomesIll cardiac patientsManagement of patientsAcute cardiac diseaseAcute myocardial infarctionDirect cellular toxicityCoronary vasoconstrictionPulmonary hypertensionRespiratory failureHemodynamic effectsHeart failureOxygen therapyClinical outcomesSupplemental oxygenAvailable trialsCardiac arrestMyocardial infarctionCardiac patientsCardiac diseaseClinical practiceCardiovascular systemHyperoxia
2015
Predictors of warfarin‐associated adverse events in hospitalized patients: Opportunities to prevent patient harm
Metersky ML, Eldridge N, Wang Y, Jaser L, Bona R, Eckenrode S, Bakullari A, Andrawis M, Classen D, Krumholz HM. Predictors of warfarin‐associated adverse events in hospitalized patients: Opportunities to prevent patient harm. Journal Of Hospital Medicine 2015, 11: 276-282. PMID: 26662851, DOI: 10.1002/jhm.2528.Peer-Reviewed Original ResearchConceptsAdverse eventsWarfarin-related adverse eventsHospitalized patientsOdds ratioINR monitoringPneumonia patientsINR measurementsFrequent INR monitoringPredictors of warfarinRetrospective cohort studyAcute cardiac diseaseAcute care hospitalsFrequency of warfarinCohort studyCare hospitalSurgical patientsCardiac patientsCardiac diseasePatientsPatient harmWarfarinSignificant associationINRMore daysMonitoring System data
2007
Acute Coronary Care in the Elderly, Part I
Alexander KP, Newby LK, Cannon CP, Armstrong PW, Gibler WB, Rich MW, Van de Werf F, White HD, Weaver WD, Naylor MD, Gore JM, Krumholz HM, Ohman EM. Acute Coronary Care in the Elderly, Part I. Circulation 2007, 115: 2549-2569. PMID: 17502590, DOI: 10.1161/circulationaha.107.182615.Peer-Reviewed Original ResearchMeSH KeywordsAcute DiseaseAge FactorsAgedAged, 80 and overAngina, UnstableAngioplasty, Balloon, CoronaryAnticoagulantsCardiac CatheterizationClinical Trials as TopicComorbidityCreatinineDisease ManagementDisease SusceptibilityDose-Response Relationship, DrugEvidence-Based MedicineFemaleHospital MortalityHumansKidneyLife ExpectancyMaleMetabolic Clearance RateMulticenter Studies as TopicMyocardial InfarctionPlatelet Aggregation InhibitorsPractice Guidelines as TopicRegistriesRisk AssessmentRisk FactorsStentsTreatment OutcomeConceptsAcute coronary syndromeElderly patientsOlder patientsInvasive treatmentSegment elevation acute coronary syndromesAmerican Heart Association scientific statementST-segment elevation myocardial infarctionElevation acute coronary syndromeComplex health statusAcute coronary careSubset of patientsAcute cardiac diseaseAge subgroup analysisTreatment-related benefitsGuideline-based careTreatment-related risksOutcomes of importanceQuality of lifeLimited trial dataCommunity practiceBasis of ageApplication of evidenceHigher disease riskGeriatric perspectiveCoronary syndrome
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