Depletion of Undecaprenyl Pyrophosphate Phosphatases Disrupts Cell Envelope Biogenesis in Bacillus subtilis
Zhao H, Sun Y, Peters J, Gross C, Garner E, Helmann J. Depletion of Undecaprenyl Pyrophosphate Phosphatases Disrupts Cell Envelope Biogenesis in Bacillus subtilis. Journal Of Bacteriology 2016, 198: 2925-2935. PMID: 27528508, PMCID: PMC5055597, DOI: 10.1128/jb.00507-16.Peer-Reviewed Original ResearchConceptsUndecaprenyl pyrophosphateCRISPRi systemCell envelope stress responseSynthetic lethal gene pairsTranscriptional repression systemWall teichoic acid synthesisBacillus subtilisEnvelope stress responseCell envelope biogenesisCell envelope synthesisSet of genesLipid II cycleLipid-linked precursorsShort palindromic repeats (CRISPR) systemTeichoic acid synthesisPalindromic repeats systemWall teichoic acidBacterial cell envelopeHigh turgor pressureGenetic redundancyEnvelope biogenesisEssential genesLipid phosphataseRepression systemFunctional redundancyBiogenesis of the Gram-positive bacterial cell envelope
Siegel S, Liu J, Ton-That H. Biogenesis of the Gram-positive bacterial cell envelope. Current Opinion In Microbiology 2016, 34: 31-37. PMID: 27497053, PMCID: PMC5164837, DOI: 10.1016/j.mib.2016.07.015.Peer-Reviewed Original ResearchConceptsWall teichoic acidGram-positive cell envelopeCell envelopeLipoteichoic acidLytR-CpsA-Psr family proteinsPhylum of Gram-positive bacteriaSortase-assembled piliCell envelope biogenesisBacterial cell envelopeGram-negative counterpartsGram-positive bacterial cell envelopeGram-positive bacteriaEnvelope biogenesisFamily proteinsTeichoic acidGram-negative organismsSurface displaySurface proteinsFolding mechanismOxidized proteinsGram-positiveCapsular polysaccharideDivergent functionsPiliBiogenesis
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