2007
Expression of beclin‐1, an autophagy‐related protein, in gastric and colorectal cancers
AHN C, JEONG E, LEE J, KIM M, KIM S, KIM S, YOO N, LEE S. Expression of beclin‐1, an autophagy‐related protein, in gastric and colorectal cancers. Apmis 2007, 115: 1344-1349. PMID: 18184403, DOI: 10.1111/j.1600-0463.2007.00858.x.Peer-Reviewed Original ResearchConceptsLoss of expressionNo significant associationExpression of Beclin-1Association of beclin-1 expressionGastric cancerNormal mucosal epithelial cellsEpithelial cellsWeak expressionBeclin-1 expressionTissue microarray approachNormal mucosal cellsBreast cancer cellsMucosal epithelial cellsHaploinsufficient tumor suppressorGastric carcinoma tissuesNormal breast cellsGastric epithelial cellsClinocopathological characteristicsTumor suppressor functionBeclin-1Colorectal carcinomaBreast cancerGastric carcinomaColorectal cancerNeo-expression
2006
Decreased expression of tumour suppressor Bax-interacting factor-1 (Bif-1), a Bax activator, in gastric carcinomas
Lee J, Jeong E, Soung Y, Nam S, Lee J, Yoo N, Lee S. Decreased expression of tumour suppressor Bax-interacting factor-1 (Bif-1), a Bax activator, in gastric carcinomas. Pathology 2006, 38: 312-315. PMID: 16916719, DOI: 10.1080/00313020600820880.Peer-Reviewed Original ResearchConceptsBif-1 expressionBax-interacting factor-1Bif-1Epithelial cellsIntrinsic pathwayIntrinsic pathway of apoptosisGastric carcinomaMalignant gastric epithelial cellsExpression of Bif-1Normal mucosal epithelial cellsNormal gastric mucosal cellsPathway of apoptosisMucosal cellsEvasion of apoptosisTissue microarray approachFactor 1Glandular epithelial cellsNormal mucosal cellsIntensity of immunostainingMucosal epithelial cellsGastric mucosal cellsHallmarks of cancerBax activationGastric epithelial cellsMicroarray approachImmunohistochemical analysis of apoptosis-inducing factor (AIF) expression in gastric carcinomas
Lee J, Jeong E, Soung Y, Kim S, Nam S, Kim S, Lee J, Yoo N, Lee S. Immunohistochemical analysis of apoptosis-inducing factor (AIF) expression in gastric carcinomas. Pathology - Research And Practice 2006, 202: 497-501. PMID: 16723191, DOI: 10.1016/j.prp.2006.03.004.Peer-Reviewed Original ResearchConceptsApoptosis-inducing factor expressionApoptosis-inducing factorExpression of apoptosis-inducing factorMalignant gastric epithelial cellsExpression patternsGastric tumorigenesisNormal gastric mucosal cellsCaspase-independent apoptosisAdvanced gastric carcinomaDeath of cellsGastric epithelial cellsMitochondrial proteinsOxidoreductase functionGastric carcinomaMucosal cellsImmunohistochemical analysisNormal mucosal cellsParietal cellsGastric parietal cellsTumorigenesisDiffuse-type cancerDepth of invasionEpithelial cellsIntestinal-type cancerGastric mucosal cells
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