2009
PI3K/Akt signalling‐mediated protein surface expression sensed by 14‐3‐3 interacting motif
Chung J, Okamoto Y, Coblitz B, Li M, Qiu Y, Shikano S. PI3K/Akt signalling‐mediated protein surface expression sensed by 14‐3‐3 interacting motif. The FEBS Journal 2009, 276: 5547-5558. PMID: 19691494, PMCID: PMC4301307, DOI: 10.1111/j.1742-4658.2009.07241.x.Peer-Reviewed Original ResearchMeSH Keywords14-3-3 ProteinsAmino Acid MotifsAmino Acid SequenceAnimalsBinding SitesCattleCell LineCell MembraneHumansMembrane ProteinsPhosphatidylinositol 3-KinasesPhosphorylationProtein BindingProto-Oncogene Proteins c-aktReceptors, G-Protein-CoupledReceptors, PeptideRecombinant Fusion ProteinsSignal TransductionTransfectionConceptsCell surface expressionMembrane proteinsEndoplasmic reticulum localization signalsSurface expressionDifferent extracellular signalsFetal bovine serumPost-translational modificationsSpecific protein localizationG protein-coupled receptorsDominant-negative AktC-terminal sequencesKinase B pathwayProtein-coupled receptorsGenetic screenCell surface membraneLocalization signalCargo proteinsActive kinaseExtracellular signalingExtracellular signalsProtein localizationProtein surface expressionKinase activityBovine serumCellular responses
1996
Protein phosphatase 2A in stretch‐induced endothelial cell proliferation
Murata K, Mills I, Sumpio B. Protein phosphatase 2A in stretch‐induced endothelial cell proliferation. Journal Of Cellular Biochemistry 1996, 63: 311-319. PMID: 8913882, DOI: 10.1002/(sici)1097-4644(19961201)63:3<311::aid-jcb6>3.0.co;2-#.Peer-Reviewed Original ResearchConceptsProtein phosphatase 2APhosphatase 2AProtein phosphatase 2A activityProtein phosphatase 1Phosphatase 2A activityProtein kinase CPhosphatase 1Bovine aortic endothelial cellsOkadaic acidGrowth suppressorEndothelial cellsKinase CEndothelial cell proliferationCell growthFetal bovine serumCellular proliferationAortic endothelial cellsCell proliferationCyclic strainBovine serumKey mechanismProliferationCellsStrainsSuppressor
1992
Isolation and characterization of rabbit cardiac endothelial cells: Response to cyclic strain and growth factors in vitro
Widmann M, Letsou G, Phan S, Baldwin J, Sumpio B. Isolation and characterization of rabbit cardiac endothelial cells: Response to cyclic strain and growth factors in vitro. Journal Of Surgical Research 1992, 53: 331-334. PMID: 1405613, DOI: 10.1016/0022-4804(92)90057-7.Peer-Reviewed Original ResearchConceptsRetina-derived growth factorCardiac endothelial cellsEndothelial cellsGrowth factorPure endothelial cellsEC proliferationProliferative responseExogenous growth factorsTrophic effectsRabbit heartsAcetylated LDLCardiac endotheliumCollagenase digestionFetal bovine serumPulsatile strainSignificant increaseBovine serumProliferationEC morphologyCellsRegimenResponseLDLEndotheliumFactors
1983
Ciliary epithelia of the mammalian eye in cultured explants
Kondo K, Coca-Prados M, Sears M. Ciliary epithelia of the mammalian eye in cultured explants. Cell And Tissue Research 1983, 233: 629-638. PMID: 6627352, DOI: 10.1007/bf00212230.Peer-Reviewed Original ResearchConceptsPigment granulesCultured explantsDulbecco's Modified Eagle's MediumFocal junctionsColumnar cellsFetal bovine serumJunctional complexesCuboidal cellsMammalian eyeCiliary epitheliumChannel-like structuresEpithelial cellsPlastic culture dishesNonpigmented cellsExplantsCellsBovine serumUltrastructural characteristicsOutermost layerPlastic dishesModified Eagle MediumPigmented epitheliumBasement membraneEagle's mediumCulture dishes
1982
The influence of retinoids on cultivated human keratinocytes
McGuire J, Fedarko N, Johanssen E, LaVigne J, Lyons G, Milstone L, Osber M. The influence of retinoids on cultivated human keratinocytes. Journal Of The American Academy Of Dermatology 1982, 6: 630-639. PMID: 6175669, DOI: 10.1016/s0190-9622(82)70052-0.Peer-Reviewed Original ResearchConceptsInfluence of retinoidsFetal bovine serumStratified squamous epitheliumTrans retinoic acidInteraction of keratinocytesSquamous epitheliumBovine serumVitamin AVitamin A.Cultured keratinocytesHuman keratinocytesRetinoidsKeratinocytesEagle's mediumSerumKeratin polypeptidesFormation of coloniesHigh levels
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