2009
Interleukin-17 and Interferon-γ Are Produced Concomitantly by Human Coronary Artery–Infiltrating T Cells and Act Synergistically on Vascular Smooth Muscle Cells
Eid RE, Rao DA, Zhou J, Lo SF, Ranjbaran H, Gallo A, Sokol SI, Pfau S, Pober JS, Tellides G. Interleukin-17 and Interferon-γ Are Produced Concomitantly by Human Coronary Artery–Infiltrating T Cells and Act Synergistically on Vascular Smooth Muscle Cells. Circulation 2009, 119: 1424-1432. PMID: 19255340, PMCID: PMC2898514, DOI: 10.1161/circulationaha.108.827618.Peer-Reviewed Original ResearchMeSH KeywordsAdultAgedCD4-Positive T-LymphocytesCells, CulturedChemokine CXCL10Coronary Artery DiseaseCoronary VesselsFemaleGene Expression RegulationHumansInflammation MediatorsInterferon-gammaInterleukin-17Interleukin-6Interleukin-8InterleukinsMaleMiddle AgedMuscle, Smooth, VascularMyocytes, Smooth MuscleReceptors, InterferonReceptors, Interleukin-17Signal TransductionT-Lymphocyte SubsetsTransforming Growth Factor beta1VasculitisConceptsVascular smooth muscle cellsSmooth muscle cellsIL-17IFN-gammaT cellsCoronary atherosclerosisMuscle cellsCoronary arteryIL-6Signature cytokinesIL-17 plasma levelsCultured vascular smooth muscle cellsIL-17 synthesisIL-17 responsesHuman coronary atherosclerosisIL-17 secretionSubset of patientsIL-17 producersT helper cellsIFN-gamma synthesisIFN-gamma producersYoung healthy individualsAtherosclerotic coronary arteriesHuman coronary arteriesTh17 cells
2006
Daytime napping after a night of sleep loss decreases sleepiness, improves performance, and causes beneficial changes in cortisol and interleukin-6 secretion
Vgontzas A, Pejovic S, Zoumakis E, Lin H, Bixler E, Basta M, Fang J, Sarrigiannidis A, Chrousos G. Daytime napping after a night of sleep loss decreases sleepiness, improves performance, and causes beneficial changes in cortisol and interleukin-6 secretion. AJP Endocrinology And Metabolism 2006, 292: e253-e261. PMID: 16940468, DOI: 10.1152/ajpendo.00651.2005.Peer-Reviewed Original ResearchConceptsMultiple sleep latency testIL-6Night of sleep lossPsychomotor vigilance taskSleep lossLevels of IL-6Sleep latency testIL-6 levelsInterleukin-6 secretionSuppression of IL-6 secretionIL-6 secretionDaytime nappingImprove alertnessNight of total sleep lossYoung healthy individualsLatency testProlonged suppressionInflammatory cytokinesTotal sleep lossInterleukin-6Cortisol secretionHealthy individualsInsulin resistanceTransient increaseBlood samples
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