2018
Auditory and Visual Oddball Stimulus Processing Deficits in Schizophrenia and the Psychosis Risk Syndrome: Forecasting Psychosis Risk With P300
Hamilton HK, Woods SW, Roach BJ, Llerena K, McGlashan TH, Srihari VH, Ford JM, Mathalon DH. Auditory and Visual Oddball Stimulus Processing Deficits in Schizophrenia and the Psychosis Risk Syndrome: Forecasting Psychosis Risk With P300. Schizophrenia Bulletin 2018, 45: 1068-1080. PMID: 30753731, PMCID: PMC6737543, DOI: 10.1093/schbul/sby167.Peer-Reviewed Original ResearchConceptsPsychosis risk syndromeTarget P3bProcessing deficitsPsychosis onsetEvent-related potential componentP300 event-related potential componentTarget P3b amplitudesPsychosis riskInfrequent target stimuliVisual oddball taskPRS participantsHealthy control participantsP3b amplitudeVisual modalityTarget stimuliP3a amplitudeSchizophrenia participantsOddball taskNovel stimuliP300 amplitudeHC participantsRisk syndromeP3bVulnerability markerControl participants
2016
Regulating task-monitoring systems in response to variable reward contingencies and outcomes in cocaine addicts
Morie KP, De Sanctis P, Garavan H, Foxe JJ. Regulating task-monitoring systems in response to variable reward contingencies and outcomes in cocaine addicts. Psychopharmacology 2016, 233: 1105-1118. PMID: 26861797, DOI: 10.1007/s00213-015-4191-8.Peer-Reviewed Original ResearchConceptsReward processingTask successConsummatory reward processingEvent-related potentialsSpeeded response taskValue of rewardsMeasures of anhedoniaCocaine usersNeural measuresReward contingenciesPredictive cuesReward motivationReward receiptReward outcomesTask contingenciesResponse taskActive cocaine abusersReward probabilityHedonic toneAnticipatory responsesVulnerability markerReward scheduleMonitoring deficienciesAnhedoniaReward
2008
Nicotinic receptor dysfunction in major depressive disorder: A trait vulnerability marker of depression
Bhagwagar Z, Esterlis I, Ruf B, Muralidharan A, Lorberg B, Saricicek A, Bois F, Tamagnan G, Seibyl J, Staley J. Nicotinic receptor dysfunction in major depressive disorder: A trait vulnerability marker of depression. NeuroImage 2008, 41: t176. DOI: 10.1016/j.neuroimage.2008.04.143.Peer-Reviewed Original Research
2004
Attention and memory biases in the offspring of parents with bipolar disorder: indications from a pilot study
Gotlib I, Traill S, Montoya R, Joormann J, Chang K. Attention and memory biases in the offspring of parents with bipolar disorder: indications from a pilot study. Journal Of Child Psychology And Psychiatry 2004, 46: 84-93. PMID: 15660646, DOI: 10.1111/j.1469-7610.2004.00333.x.Peer-Reviewed Original ResearchConceptsLow-risk childrenNegative wordsEmotional disordersBipolar parentsEmotion Stroop taskNegative mood inductionPotential vulnerability markerBipolar disorderMood disordersAttentional biasMemory biasesCognitive vulnerabilityStroop taskEmotional stimuliMood inductionCognitive schemasCognitive structuresSad moodTime of testingBetter recallDepressed adultsVulnerability markerHigh-risk childrenControl parentsOffspring of parents
1999
Transient Depressive Relapse Induced by Catecholamine Depletion: Potential Phenotypic Vulnerability Marker?
Berman RM, Narasimhan M, Miller HL, Anand A, Cappiello A, Oren DA, Heninger GR, Charney DS. Transient Depressive Relapse Induced by Catecholamine Depletion: Potential Phenotypic Vulnerability Marker? JAMA Psychiatry 1999, 56: 395-403. PMID: 10232292, DOI: 10.1001/archpsyc.56.5.395.Peer-Reviewed Original ResearchConceptsCatecholamine depletionMedication-free subjectsMajor depressionHamilton Depression Rating Scale scoresDepression Rating Scale scoresBaseline plasma cortisol levelsDepressive reactionsSignificant depressive symptomsRating Scale scoresHistory of depressionState-related alterationsPlasma cortisol levelsCatecholamine functionAlpha-methylparatyrosineRelapse criteriaBlood samplesDepressive symptomsCortisol levelsCrossover designScale scoreDepressed subjectsReliable markerTransient increaseVulnerability markerAnxiety symptoms
1994
Affective Reactivity of Language in Stable Schizophrenic Outpatients and Their Parents
DOCHERTY N, SLEDGE W, WEXLER B. Affective Reactivity of Language in Stable Schizophrenic Outpatients and Their Parents. The Journal Of Nervous And Mental Disease 1994, 182: 313-318. PMID: 8201302, DOI: 10.1097/00005053-199406000-00001.Peer-Reviewed Original Research
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