2018
Cell-Penetrating Peptide Mediates Intracellular Membrane Passage of Human Papillomavirus L2 Protein to Trigger Retrograde Trafficking
Zhang P, da Silva G, Deatherage C, Burd C, DiMaio D. Cell-Penetrating Peptide Mediates Intracellular Membrane Passage of Human Papillomavirus L2 Protein to Trigger Retrograde Trafficking. Cell 2018, 174: 1465-1476.e13. PMID: 30122350, PMCID: PMC6128760, DOI: 10.1016/j.cell.2018.07.031.Peer-Reviewed Original ResearchMeSH KeywordsAmino Acid SequenceCapsid ProteinsCell-Penetrating PeptidesEndosomesGolgi ApparatusGreen Fluorescent ProteinsHEK293 CellsHeLa CellsHuman papillomavirus 16HumansMutagenesisOncogene Proteins, ViralProtein TransportRecombinant Fusion ProteinsSequence AlignmentVirus AttachmentVirus InternalizationConceptsCell-penetrating peptidesTrans-Golgi networkNormal cell physiologyL2 proteinRetrograde transport pathwayShort protein segmentsHPV L2 proteinTrafficking factorsRetrograde traffickingCationic cell-penetrating peptidesCell physiologyEndosomal membranesProtein segmentsC-terminusBiological roleNon-enveloped virusesRetrograde pathwayL2 capsid proteinsMembrane passageCell penetrating peptideCapsid proteinViral proteinsProteinRetromerTransport pathways
2017
The cellular endosomal protein stannin inhibits intracellular trafficking of human papillomavirus during virus entry
Lipovsky A, Erden A, Kanaya E, Zhang W, Crite M, Bradfield C, MacMicking J, DiMaio D, Schoggins JW, Iwasaki A. The cellular endosomal protein stannin inhibits intracellular trafficking of human papillomavirus during virus entry. Journal Of General Virology 2017, 98: 2821-2836. PMID: 29058661, PMCID: PMC5845663, DOI: 10.1099/jgv.0.000954.Peer-Reviewed Original ResearchConceptsHuman papillomavirusEntry of HPVVirus entryImportant infectious causeL1 major capsid proteinHPV typesTrans-Golgi networkInfectious causesProphylactic vaccinesHPV16 infectionL2 minor capsid proteinHPV entryDeadly cancerHPV16 entryBasal levelsInfectionVirus uptakeRetrograde transportHuman keratinocytesCapsid proteinHPV16PapillomavirusVirus uncoatingNon-enveloped virusesVirus
2014
Parvoviridae: General Features☆
Cotmore S, Tattersall P. Parvoviridae: General Features☆. 2014 DOI: 10.1016/b978-0-12-801238-3.02641-6.Peer-Reviewed Original Research
2000
Safety and efficacy of solvent/detergent‐treated antihaemophilic factor with an added 80 °C terminal dry heat treatment in patients with haemophilia A
Powell J, Bush M, Harrison J, Abildgaard C, Vosburgh E, Thompson A, Hurst D. Safety and efficacy of solvent/detergent‐treated antihaemophilic factor with an added 80 °C terminal dry heat treatment in patients with haemophilia A. Haemophilia 2000, 6: 140-149. PMID: 10792471, DOI: 10.1046/j.1365-2516.2000.00407.x.Peer-Reviewed Original ResearchConceptsHeat-treated preparationsPlasma-derived factor VIII concentrateCrossover pharmacokinetic studyFactor VIII inhibitorsHome treatment programHemophilia A patientsTerminal dry heat treatmentFactor VIII concentrateViral inactivation processesSolvent/detergent treatmentA patientsFactor VIII preparationsClinical parametersVIII inhibitorsHaemophilia treatmentPatientsHemophilia AVIII concentrateTreatment programRare reportsAntihaemophilic factorPharmacokinetic studyDevelopment of inhibitorsTreatmentNon-enveloped viruses
This site is protected by hCaptcha and its Privacy Policy and Terms of Service apply