Safety and efficacy of solvent/detergent‐treated antihaemophilic factor with an added 80 °C terminal dry heat treatment in patients with haemophilia A
Powell J, Bush M, Harrison J, Abildgaard C, Vosburgh E, Thompson A, Hurst D. Safety and efficacy of solvent/detergent‐treated antihaemophilic factor with an added 80 °C terminal dry heat treatment in patients with haemophilia A. Haemophilia 2000, 6: 140-149. PMID: 10792471, DOI: 10.1046/j.1365-2516.2000.00407.x.Peer-Reviewed Original ResearchConceptsHeat-treated preparationsPlasma-derived factor VIII concentrateCrossover pharmacokinetic studyFactor VIII inhibitorsHome treatment programHemophilia A patientsTerminal dry heat treatmentFactor VIII concentrateViral inactivation processesSolvent/detergent treatmentA patientsFactor VIII preparationsClinical parametersVIII inhibitorsHaemophilia treatmentPatientsHemophilia AVIII concentrateTreatment programRare reportsAntihaemophilic factorPharmacokinetic studyDevelopment of inhibitorsTreatmentNon-enveloped viruses
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