2025
Mixed Autoimmune Hemolytic Anemia: A Systematic Review of Epidemiology, Clinical Characteristics, Therapies, and Outcomes
Jacobs J, Raza S, Clark L, Stephens L, Allen E, Woo J, Walden R, Villalba C, Tormey C, Stanek C, Adkins B, Bloch E, Booth G. Mixed Autoimmune Hemolytic Anemia: A Systematic Review of Epidemiology, Clinical Characteristics, Therapies, and Outcomes. American Journal Of Hematology 2025, 100: 1397-1407. PMID: 40392014, PMCID: PMC12232602, DOI: 10.1002/ajh.27721.Peer-Reviewed Original ResearchAutoimmune hemolytic anemiaDiagnostic criteriaClinical characteristicsMixed autoimmune hemolytic anemiaMultiple lines of therapyComplex hematological disorderLines of therapyNadir hemoglobin levelsReview of epidemiologyInnovative treatment modalitiesEvaluate epidemiological patternsFrequent underlying etiologyCombination therapyHematologic malignanciesImprove patient outcomesFemale predominanceHematological disordersMulticenter studyChronic hemolysisClinical featuresTreatment modalitiesHemoglobin levelsUnderlying etiologyHemolytic anemiaAutoimmune diseasesRecent advances in the management of pediatric cholestatic liver diseases
Mysore K, Cheng K, Suri L, Fawaz R, Mavis A, Kogan‐Liberman D, Mohammad S, Taylor S. Recent advances in the management of pediatric cholestatic liver diseases. Journal Of Pediatric Gastroenterology And Nutrition 2025, 80: 549-558. PMID: 39840645, PMCID: PMC11961318, DOI: 10.1002/jpn3.12462.Peer-Reviewed Original ResearchPediatric cholestatic liver diseasesCholestatic liver diseaseIleal bile acid transporterAlagille syndromeSlow disease progressionLiver diseaseBile acid transporterMedical therapyIleal bile acid transporter inhibitorClinical trialsDisease progressionProgressive familial intrahepatic cholestasisFamilial intrahepatic cholestasisPediatric liver transplantationBile acid toxicityCurative medical therapyAcid transportImprove patient qualityIntrahepatic cholestasisBiliary atresiaSurgical managementRare conditionLiver transplantationNutritional supportUnderlying etiology
2023
Features Linked to Treatment Outcomes in Behavioral Addictions and Related Disorders
Mestre-Bach G, Potenza M. Features Linked to Treatment Outcomes in Behavioral Addictions and Related Disorders. International Journal Of Environmental Research And Public Health 2023, 20: 2873. PMID: 36833569, PMCID: PMC9957199, DOI: 10.3390/ijerph20042873.Peer-Reviewed Reviews, Practice Guidelines, Standards, and Consensus Statements
2022
Acute symptomatic seizures: an educational, evidence‐based review
Mauritz M, Hirsch LJ, Camfield P, Chin R, Nardone R, Lattanzi S, Trinka E. Acute symptomatic seizures: an educational, evidence‐based review. Epileptic Disorders 2022, 24: 26-49. PMID: 34789447, DOI: 10.1684/epd.2021.1376.Peer-Reviewed Original Research
2019
The utility of bronchoscopy in immunocompromised patients: a review
Morton C, Puchalski J. The utility of bronchoscopy in immunocompromised patients: a review. Journal Of Thoracic Disease 2019, 11: 5603-5612. PMID: 32030281, PMCID: PMC6988056, DOI: 10.21037/jtd.2019.09.72.Peer-Reviewed Original ResearchAddition of biopsiesTiming of bronchoscopyNon-infectious etiologiesRole of bronchoscopyNon-infectious pulmonary diseasesUtility of bronchoscopyPrescription drug useNon-invasive testingImmunocompromised stateInfectious complicationsPulmonary diseaseMedical managementUnderlying etiologyPulmonary disordersHematologic malignanciesDiagnostic yieldBronchoscopyDrug usePatientsEtiologyDisordersOngoing roleChemotherapyComplicationsLavageAssociation Between Diaphragmatic Paralysis and Ipsilateral Cervical Spondylosis on MRI
O’Beirne S, Chazen JL, Cornman-Homonoff J, Carey BT, Gelbman BD. Association Between Diaphragmatic Paralysis and Ipsilateral Cervical Spondylosis on MRI. Lung 2019, 197: 727-733. PMID: 31535202, DOI: 10.1007/s00408-019-00271-y.Peer-Reviewed Original ResearchConceptsCervical spine magnetic resonance imagingMagnetic resonance imagingSpine magnetic resonance imagingCervical spondylosisCervical spineUnderrecognized causeContralateral foraminal stenosisCervical spine levelsDiaphragmatic paralysisDiaphragmatic dysfunctionNeuroforaminal stenosisTotal cohortForaminal stenosisRetrospective studyUnderlying etiologySpine levelImportant causeOverall severityResonance imagingEtiologySeveritySpineSpondylosisStenosisC4-C5
2018
De novo pathogenic variants in neuronal differentiation factor 2 (NEUROD2) cause a form of early infantile epileptic encephalopathy
Sega AG, Mis EK, Lindstrom K, Mercimek-Andrews S, Ji W, Cho MT, Juusola J, Konstantino M, Jeffries L, Khokha MK, Lakhani SA. De novo pathogenic variants in neuronal differentiation factor 2 (NEUROD2) cause a form of early infantile epileptic encephalopathy. Journal Of Medical Genetics 2018, 56: 113. PMID: 30323019, DOI: 10.1136/jmedgenet-2018-105322.Peer-Reviewed Original ResearchConceptsEarly infantile epileptic encephalopathyInfantile epileptic encephalopathyEpileptic encephalopathyPatient variantsDe novo pathogenic variantsNovel de novo variantNovo pathogenic variantsEarly-onset refractory seizuresDifferentiation factor 2Whole-exome sequencingNeuronal differentiation factorRefractory seizuresSignificant developmental delaySpontaneous seizuresUnderlying etiologyEctopic neuronsDe novo variantsPatient's conditionEncephalopathyPathogenic variantsSevere disordersDevelopmental delayUnrelated childrenExome sequencingGene mutations
2014
Cardiac Arrest during Hospitalization for Delivery in the United States, 1998–2011
Mhyre JM, Tsen LC, Einav S, Kuklina EV, Leffert LR, Bateman BT. Cardiac Arrest during Hospitalization for Delivery in the United States, 1998–2011. Anesthesiology 2014, 120: 810-818. PMID: 24694844, PMCID: PMC4445354, DOI: 10.1097/aln.0000000000000159.Peer-Reviewed Original ResearchConceptsAmniotic fluid embolismCardiac arrestPotential etiologiesHeart failureCommon potential etiologyMaternal cardiac arrestNationwide Inpatient SampleDemographic risk factorsMaternal cardiopulmonary arrestHospital dischargeCardiopulmonary arrestU.S. hospitalizationsUnderlying etiologyInpatient SampleMaternal arrestRisk factorsHospitalizationSurvival rateEtiologySepsisEmbolismHemorrhageArrestPatientsSurvival
2011
Gain of function NaV1.7 mutations in idiopathic small fiber neuropathy
Faber CG, Hoeijmakers JG, Ahn H, Cheng X, Han C, Choi J, Estacion M, Lauria G, Vanhoutte EK, Gerrits MM, Dib‐Hajj S, Drenth JP, Waxman SG, Merkies IS. Gain of function NaV1.7 mutations in idiopathic small fiber neuropathy. Annals Of Neurology 2011, 71: 26-39. PMID: 21698661, DOI: 10.1002/ana.22485.Peer-Reviewed Original ResearchConceptsSmall nerve fibre neuropathyIntraepidermal nerve fiber densityQuantitative sensory testingSmall-diameter peripheral axonsDorsal root ganglion neuronsGanglion neuronsPeripheral axonsSodium channelsAbnormal intraepidermal nerve fibre densityAbnormal quantitative sensory testingIdiopathic small fiber neuropathyFunction Nav1.7 mutationsNerve conduction studiesNerve fiber densitySmall fiber neuropathyVoltage-gated sodium channelsRare genetic syndromeExpression of gainTendon reflexesConduction studiesNav1.7 mutationUnderlying etiologyVibration senseSensory testingPatients
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